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Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.
Workman MJ, Mahe MM, Trisno S, Poling HM, Watson CL, Sundaram N, Chang CF, Schiesser J, Aubert P, Stanley EG, Elefanty AG, Miyaoka Y, Mandegar MA, Conklin BR, Neunlist M, Brugmann SA, Helmrath MA, Wells JM. Workman MJ, et al. Among authors: sundaram n. Nat Med. 2017 Jan;23(1):49-59. doi: 10.1038/nm.4233. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869805 Free PMC article.
Intestinal crypts reproducibly expand in culture.
Fuller MK, Faulk DM, Sundaram N, Shroyer NF, Henning SJ, Helmrath MA. Fuller MK, et al. Among authors: sundaram n. J Surg Res. 2012 Nov;178(1):48-54. doi: 10.1016/j.jss.2012.03.037. Epub 2012 Apr 10. J Surg Res. 2012. PMID: 22564827 Free PMC article.
Intestinal stem cells remain viable after prolonged tissue storage.
Fuller MK, Faulk DM, Sundaram N, Mahe MM, Stout KM, von Furstenberg RJ, Smith BJ, McNaughton KK, Shroyer NF, Helmrath MA, Henning SJ. Fuller MK, et al. Among authors: sundaram n. Cell Tissue Res. 2013 Nov;354(2):441-50. doi: 10.1007/s00441-013-1674-y. Epub 2013 Jul 3. Cell Tissue Res. 2013. PMID: 23820734 Free PMC article.
An in vivo model of human small intestine using pluripotent stem cells.
Watson CL, Mahe MM, Múnera J, Howell JC, Sundaram N, Poling HM, Schweitzer JI, Vallance JE, Mayhew CN, Sun Y, Grabowski G, Finkbeiner SR, Spence JR, Shroyer NF, Wells JM, Helmrath MA. Watson CL, et al. Among authors: sundaram n. Nat Med. 2014 Nov;20(11):1310-4. doi: 10.1038/nm.3737. Epub 2014 Oct 19. Nat Med. 2014. PMID: 25326803 Free PMC article.
Drug-induced secretory diarrhea: A role for CFTR.
Moon C, Zhang W, Sundaram N, Yarlagadda S, Reddy VS, Arora K, Helmrath MA, Naren AP. Moon C, et al. Among authors: sundaram n. Pharmacol Res. 2015 Dec;102:107-112. doi: 10.1016/j.phrs.2015.08.024. Epub 2015 Sep 30. Pharmacol Res. 2015. PMID: 26429773 Free PMC article. Review.
Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells.
Nalapareddy K, Nattamai KJ, Kumar RS, Karns R, Wikenheiser-Brokamp KA, Sampson LL, Mahe MM, Sundaram N, Yacyshyn MB, Yacyshyn B, Helmrath MA, Zheng Y, Geiger H. Nalapareddy K, et al. Among authors: sundaram n. Cell Rep. 2017 Mar 14;18(11):2608-2621. doi: 10.1016/j.celrep.2017.02.056. Cell Rep. 2017. PMID: 28297666 Free PMC article.
CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.
Bertaux-Skeirik N, Wunderlich M, Teal E, Chakrabarti J, Biesiada J, Mahe M, Sundaram N, Gabre J, Hawkins J, Jian G, Engevik AC, Yang L, Wang J, Goldenring JR, Qualls JE, Medvedovic M, Helmrath MA, Diwan T, Mulloy JC, Zavros Y. Bertaux-Skeirik N, et al. Among authors: sundaram n. J Pathol. 2017 Aug;242(4):463-475. doi: 10.1002/path.4918. J Pathol. 2017. PMID: 28497484 Free PMC article.
Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.
Múnera JO, Sundaram N, Rankin SA, Hill D, Watson C, Mahe M, Vallance JE, Shroyer NF, Sinagoga KL, Zarzoso-Lacoste A, Hudson JR, Howell JC, Chatuvedi P, Spence JR, Shannon JM, Zorn AM, Helmrath MA, Wells JM. Múnera JO, et al. Among authors: sundaram n. Cell Stem Cell. 2017 Jul 6;21(1):51-64.e6. doi: 10.1016/j.stem.2017.05.020. Epub 2017 Jun 22. Cell Stem Cell. 2017. PMID: 28648364 Free PMC article.
An Organoid-Based Preclinical Model of Human Gastric Cancer.
Steele NG, Chakrabarti J, Wang J, Biesiada J, Holokai L, Chang J, Nowacki LM, Hawkins J, Mahe M, Sundaram N, Shroyer N, Medvedovic M, Helmrath M, Ahmad S, Zavros Y. Steele NG, et al. Among authors: sundaram n. Cell Mol Gastroenterol Hepatol. 2019;7(1):161-184. doi: 10.1016/j.jcmgh.2018.09.008. Epub 2018 Sep 20. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30522949 Free PMC article.
135 results