Agarwal SK - Search Results

1

Effect of ketoconazole, a strong CYP3A inhibitor, on the pharmacokinetics of venetoclax, a BCL-2 inhibitor, in patients with non-Hodgkin lymphoma.

Agarwal SK, Salem AH, Danilov AV, Hu B, Puvvada S, Gutierrez M, Chien D, Lewis LD, Wong SL. Agarwal SK, et al. Br J Clin Pharmacol. 2017 Apr;83(4):846-854. doi: 10.1111/bcp.13175. Epub 2017 Jan 18. Br J Clin Pharmacol. 2017. PMID: 27859472 Free PMC article. Clinical Trial.

2

Metabolism and Disposition of a Novel B-Cell Lymphoma-2 Inhibitor Venetoclax in Humans and Characterization of Its Unusual Metabolites.

Liu H, Michmerhuizen MJ, Lao Y, Wan K, Salem AH, Sawicki J, Serby M, Vaidyanathan S, Wong SL, Agarwal S, Dunbar M, Sydor J, de Morais SM, Lee AJ. Liu H, et al. Drug Metab Dispos. 2017 Mar;45(3):294-305. doi: 10.1124/dmd.116.071613. Epub 2016 Dec 19. Drug Metab Dispos. 2017. PMID: 27993930 Clinical Trial.

3

Evaluation of Rifampin's Transporter Inhibitory and CYP3A Inductive Effects on the Pharmacokinetics of Venetoclax, a BCL-2 Inhibitor: Results of a Single- and Multiple-Dose Study.

Agarwal SK, Hu B, Chien D, Wong SL, Salem AH. Agarwal SK, et al. J Clin Pharmacol. 2016 Nov;56(11):1335-1343. doi: 10.1002/jcph.730. J Clin Pharmacol. 2016. PMID: 26953185 Clinical Trial.

4

Effect of Low- and High-Fat Meals on the Pharmacokinetics of Venetoclax, a Selective First-in-Class BCL-2 Inhibitor.

Salem AH, Agarwal SK, Dunbar M, Nuthalapati S, Chien D, Freise KJ, Wong SL. Salem AH, et al. Among authors: agarwal sk. J Clin Pharmacol. 2016 Nov;56(11):1355-1361. doi: 10.1002/jcph.741. J Clin Pharmacol. 2016. PMID: 27029823 Clinical Trial.

5

Clinical Predictors of Venetoclax Pharmacokinetics in Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma Patients: a Pooled Population Pharmacokinetic Analysis.

Jones AK, Freise KJ, Agarwal SK, Humerickhouse RA, Wong SL, Salem AH. Jones AK, et al. Among authors: agarwal sk. AAPS J. 2016 Sep;18(5):1192-1202. doi: 10.1208/s12248-016-9927-9. Epub 2016 May 27. AAPS J. 2016. PMID: 27233802 Clinical Trial.

6

Pharmacokinetics of Venetoclax, a Novel BCL-2 Inhibitor, in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Non-Hodgkin Lymphoma.

Salem AH, Agarwal SK, Dunbar M, Enschede SL, Humerickhouse RA, Wong SL. Salem AH, et al. Among authors: agarwal sk. J Clin Pharmacol. 2017 Apr;57(4):484-492. doi: 10.1002/jcph.821. Epub 2016 Nov 15. J Clin Pharmacol. 2017. PMID: 27558232

7

Evaluation of the Pharmacokinetic Interaction between Venetoclax, a Selective BCL-2 Inhibitor, and Warfarin in Healthy Volunteers.

Salem AH, Hu B, Freise KJ, Agarwal SK, Sidhu DS, Wong SL. Salem AH, et al. Among authors: agarwal sk. Clin Drug Investig. 2017 Mar;37(3):303-309. doi: 10.1007/s40261-016-0485-9. Clin Drug Investig. 2017. PMID: 27910036 Clinical Trial.

8

Management of Venetoclax-Posaconazole Interaction in Acute Myeloid Leukemia Patients: Evaluation of Dose Adjustments.

Agarwal SK, DiNardo CD, Potluri J, Dunbar M, Kantarjian HM, Humerickhouse RA, Wong SL, Menon RM, Konopleva MY, Salem AH. Agarwal SK, et al. Clin Ther. 2017 Feb;39(2):359-367. doi: 10.1016/j.clinthera.2017.01.003. Epub 2017 Feb 1. Clin Ther. 2017. PMID: 28161120 Clinical Trial.

9

Pharmacokinetics of venetoclax in patients with 17p deletion chronic lymphocytic leukemia.

Salem AH, Dunbar M, Agarwal SK. Salem AH, et al. Among authors: agarwal sk. Anticancer Drugs. 2017 Sep;28(8):911-914. doi: 10.1097/CAD.0000000000000522. Anticancer Drugs. 2017. PMID: 28562380 Clinical Trial.

10

Pharmacokinetics of the BCL-2 Inhibitor Venetoclax in Healthy Chinese Subjects.

Cheung TT, Salem AH, Menon RM, Munasinghe WP, Bueno OF, Agarwal SK. Cheung TT, et al. Among authors: agarwal sk. Clin Pharmacol Drug Dev. 2018 May;7(4):435-440. doi: 10.1002/cpdd.395. Epub 2017 Oct 23. Clin Pharmacol Drug Dev. 2018. PMID: 29058801 Clinical Trial.

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