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Page 1
Cardioprotection and lifespan extension by the natural polyamine spermidine.
Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F. Eisenberg T, et al. Among authors: stekovic s. Nat Med. 2016 Dec;22(12):1428-1438. doi: 10.1038/nm.4222. Epub 2016 Nov 14. Nat Med. 2016. PMID: 27841876 Free PMC article.
Dietary spermidine for lowering high blood pressure.
Eisenberg T, Abdellatif M, Zimmermann A, Schroeder S, Pendl T, Harger A, Stekovic S, Schipke J, Magnes C, Schmidt A, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Carmona-Gutierrez D, Pietrocola F, Pieber TR, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F. Eisenberg T, et al. Among authors: stekovic s. Autophagy. 2017 Apr 3;13(4):767-769. doi: 10.1080/15548627.2017.1280225. Epub 2017 Jan 24. Autophagy. 2017. PMID: 28118075 Free PMC article.
Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification.
Ruckenstuhl C, Netzberger C, Entfellner I, Carmona-Gutierrez D, Kickenweiz T, Stekovic S, Gleixner C, Schmid C, Klug L, Sorgo AG, Eisenberg T, Büttner S, Mariño G, Koziel R, Jansen-Dürr P, Fröhlich KU, Kroemer G, Madeo F. Ruckenstuhl C, et al. Among authors: stekovic s. PLoS Genet. 2014 May 1;10(5):e1004347. doi: 10.1371/journal.pgen.1004347. eCollection 2014 May. PLoS Genet. 2014. PMID: 24785424 Free PMC article.
Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline.
Schwarz C, Stekovic S, Wirth M, Benson G, Royer P, Sigrist SJ, Pieber T, Dammbrueck C, Magnes C, Eisenberg T, Pendl T, Bohlken J, Köbe T, Madeo F, Flöel A. Schwarz C, et al. Among authors: stekovic s. Aging (Albany NY). 2018 Jan 8;10(1):19-33. doi: 10.18632/aging.101354. Aging (Albany NY). 2018. PMID: 29315079 Free PMC article. Clinical Trial.
Higher spermidine intake is linked to lower mortality: a prospective population-based study.
Kiechl S, Pechlaner R, Willeit P, Notdurfter M, Paulweber B, Willeit K, Werner P, Ruckenstuhl C, Iglseder B, Weger S, Mairhofer B, Gartner M, Kedenko L, Chmelikova M, Stekovic S, Stuppner H, Oberhollenzer F, Kroemer G, Mayr M, Eisenberg T, Tilg H, Madeo F, Willeit J. Kiechl S, et al. Among authors: stekovic s. Am J Clin Nutr. 2018 Aug 1;108(2):371-380. doi: 10.1093/ajcn/nqy102. Am J Clin Nutr. 2018. PMID: 29955838 Free article.
Autophagy extends lifespan via vacuolar acidification.
Ruckenstuhl C, Netzberger C, Entfellner I, Carmona-Gutierrez D, Kickenweiz T, Stekovic S, Gleixner C, Schmid C, Klug L, Hajnal I, Sorgo AG, Eisenberg T, Büttner S, Marin O G, Koziel R, Magnes C, Sinner F, Pieber TR, Jansen-Dürr P, Fröhlich KU, Kroemer G, Madeo F. Ruckenstuhl C, et al. Among authors: stekovic s. Microb Cell. 2014 May 5;1(5):160-162. doi: 10.15698/mic2014.05.147. Microb Cell. 2014. PMID: 28357240 Free PMC article.
Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial.
Schwarz C, Benson GS, Horn N, Wurdack K, Grittner U, Schilling R, Märschenz S, Köbe T, Hofer SJ, Magnes C, Stekovic S, Eisenberg T, Sigrist SJ, Schmitz D, Wirth M, Madeo F, Flöel A. Schwarz C, et al. Among authors: stekovic s. JAMA Netw Open. 2022 May 2;5(5):e2213875. doi: 10.1001/jamanetworkopen.2022.13875. JAMA Netw Open. 2022. PMID: 35616942 Free PMC article. Clinical Trial.
Cell death pathways.
Stekovic S, Madeo F. Stekovic S, et al. Biochim Biophys Acta. 2013 Dec;1833(12):3447. doi: 10.1016/j.bbamcr.2013.09.016. Biochim Biophys Acta. 2013. PMID: 24238637 Free article. No abstract available.
16 results