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Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres.
Garcia-Exposito L, Bournique E, Bergoglio V, Bose A, Barroso-Gonzalez J, Zhang S, Roncaioli JL, Lee M, Wallace CT, Watkins SC, Opresko PL, Hoffmann JS, O'Sullivan RJ. Garcia-Exposito L, et al. Among authors: hoffmann js. Cell Rep. 2016 Nov 8;17(7):1858-1871. doi: 10.1016/j.celrep.2016.10.048. Cell Rep. 2016. PMID: 27829156 Free PMC article.
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ.
Terrados G, Capp JP, Canitrot Y, García-Díaz M, Bebenek K, Kirchhoff T, Villanueva A, Boudsocq F, Bergoglio V, Cazaux C, Kunkel TA, Hoffmann JS, Blanco L. Terrados G, et al. Among authors: hoffmann js. PLoS One. 2009 Oct 6;4(10):e7290. doi: 10.1371/journal.pone.0007290. PLoS One. 2009. PMID: 19806195 Free PMC article.
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability.
Lemée F, Bergoglio V, Fernandez-Vidal A, Machado-Silva A, Pillaire MJ, Bieth A, Gentil C, Baker L, Martin AL, Leduc C, Lam E, Magdeleine E, Filleron T, Oumouhou N, Kaina B, Seki M, Grimal F, Lacroix-Triki M, Thompson A, Roché H, Bourdon JC, Wood RD, Hoffmann JS, Cazaux C. Lemée F, et al. Among authors: hoffmann js. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13390-5. doi: 10.1073/pnas.0910759107. Epub 2010 Jul 12. Proc Natl Acad Sci U S A. 2010. PMID: 20624954 Free PMC article.
108 results