Zhou Y - Search Results

1

Inhibition of RAS function through targeting an allosteric regulatory site.

Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP. Spencer-Smith R, et al. Among authors: zhou y. Nat Chem Biol. 2017 Jan;13(1):62-68. doi: 10.1038/nchembio.2231. Epub 2016 Nov 7. Nat Chem Biol. 2017. PMID: 27820802 Free PMC article.

2

The nonsteroidal anti-inflammatory drug indomethacin induces heterogeneity in lipid membranes: potential implication for its diverse biological action.

Zhou Y, Hancock JF, Lichtenberger LM. Zhou Y, et al. PLoS One. 2010 Jan 21;5(1):e8811. doi: 10.1371/journal.pone.0008811. PLoS One. 2010. PMID: 20098676 Free PMC article.

3

The anti-inflammatory drug indomethacin alters nanoclustering in synthetic and cell plasma membranes.

Zhou Y, Plowman SJ, Lichtenberger LM, Hancock JF. Zhou Y, et al. J Biol Chem. 2010 Nov 5;285(45):35188-95. doi: 10.1074/jbc.M110.141200. Epub 2010 Sep 7. J Biol Chem. 2010. PMID: 20826816 Free PMC article.

4

Nonsteroidal anti-inflammatory drugs alter the spatiotemporal organization of Ras proteins on the plasma membrane.

Zhou Y, Cho KJ, Plowman SJ, Hancock JF. Zhou Y, et al. J Biol Chem. 2012 May 11;287(20):16586-95. doi: 10.1074/jbc.M112.348490. Epub 2012 Mar 19. J Biol Chem. 2012. PMID: 22433858 Free PMC article.

5

Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells.

Zhang F, Wang Z, Lu M, Yonekubo Y, Liang X, Zhang Y, Wu P, Zhou Y, Grinstein S, Hancock JF, Du G. Zhang F, et al. Among authors: zhou y. Mol Cell Biol. 2014 Jan;34(1):84-95. doi: 10.1128/MCB.00987-13. Epub 2013 Oct 28. Mol Cell Biol. 2014. PMID: 24164897 Free PMC article.

6

Bile acids modulate signaling by functional perturbation of plasma membrane domains.

Zhou Y, Maxwell KN, Sezgin E, Lu M, Liang H, Hancock JF, Dial EJ, Lichtenberger LM, Levental I. Zhou Y, et al. J Biol Chem. 2013 Dec 13;288(50):35660-70. doi: 10.1074/jbc.M113.519116. Epub 2013 Oct 28. J Biol Chem. 2013. PMID: 24165125 Free PMC article.

7

Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters.

Zhou Y, Liang H, Rodkey T, Ariotti N, Parton RG, Hancock JF. Zhou Y, et al. Mol Cell Biol. 2014 Mar;34(5):862-76. doi: 10.1128/MCB.01227-13. Epub 2013 Dec 23. Mol Cell Biol. 2014. PMID: 24366544 Free PMC article.

8

Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling.

Ariotti N, Fernández-Rojo MA, Zhou Y, Hill MM, Rodkey TL, Inder KL, Tanner LB, Wenk MR, Hancock JF, Parton RG. Ariotti N, et al. Among authors: zhou y. J Cell Biol. 2014 Mar 3;204(5):777-92. doi: 10.1083/jcb.201307055. Epub 2014 Feb 24. J Cell Biol. 2014. PMID: 24567358 Free PMC article.

9

Ras nanoclusters: Versatile lipid-based signaling platforms.

Zhou Y, Hancock JF. Zhou Y, et al. Biochim Biophys Acta. 2015 Apr;1853(4):841-9. doi: 10.1016/j.bbamcr.2014.09.008. Epub 2014 Sep 16. Biochim Biophys Acta. 2015. PMID: 25234412 Free article. Review.

10

Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation.

Šolman M, Ligabue A, Blaževitš O, Jaiswal A, Zhou Y, Liang H, Lectez B, Kopra K, Guzmán C, Härmä H, Hancock JF, Aittokallio T, Abankwa D. Šolman M, et al. Among authors: zhou y. Elife. 2015 Aug 14;4:e08905. doi: 10.7554/eLife.08905. Elife. 2015. PMID: 26274561 Free PMC article.

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