Pendlebury DF - Search Results

1

An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis.

Kayode O, Wang R, Pendlebury DF, Cohen I, Henin RD, Hockla A, Soares AS, Papo N, Caulfield TR, Radisky ES. Kayode O, et al. Among authors: pendlebury df. J Biol Chem. 2016 Dec 16;291(51):26304-26319. doi: 10.1074/jbc.M116.758417. Epub 2016 Nov 3. J Biol Chem. 2016. PMID: 27810896 Free PMC article.

2

Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.

Pendlebury D, Wang R, Henin RD, Hockla A, Soares AS, Madden BJ, Kazanov MD, Radisky ES. Pendlebury D, et al. J Biol Chem. 2014 Nov 21;289(47):32783-97. doi: 10.1074/jbc.M114.609560. Epub 2014 Oct 9. J Biol Chem. 2014. PMID: 25301953 Free PMC article.

3

Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers.

Mehner C, Oberg AL, Kalli KR, Nassar A, Hockla A, Pendlebury D, Cichon MA, Goergen KM, Maurer MJ, Goode EL, Keeney GL, Jatoi A, Sahin-Tóth M, Copland JA, Radisky DC, Radisky ES. Mehner C, et al. Oncotarget. 2015 Nov 3;6(34):35737-54. doi: 10.18632/oncotarget.5927. Oncotarget. 2015. PMID: 26437224 Free PMC article.

4

Structure of a meiosis-specific complex central to BRCA2 localization at recombination sites.

Pendlebury DF, Zhang J, Agrawal R, Shibuya H, Nandakumar J. Pendlebury DF, et al. Nat Struct Mol Biol. 2021 Aug;28(8):671-680. doi: 10.1038/s41594-021-00635-0. Epub 2021 Aug 9. Nat Struct Mol Biol. 2021. PMID: 34373645 Free PMC article.

5

Dissecting the telomere-inner nuclear membrane interface formed in meiosis.

Pendlebury DF, Fujiwara Y, Tesmer VM, Smith EM, Shibuya H, Watanabe Y, Nandakumar J. Pendlebury DF, et al. Nat Struct Mol Biol. 2017 Dec;24(12):1064-1072. doi: 10.1038/nsmb.3493. Epub 2017 Oct 30. Nat Struct Mol Biol. 2017. PMID: 29083414 Free PMC article.

6

The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells.

Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury DF, Alam I, Livera G, Emmanuelle M, Wang PJ, Nandakumar J, Davies OR, Shibuya H. Zhang J, et al. Among authors: pendlebury df. Nat Commun. 2020 Apr 28;11(1):2055. doi: 10.1038/s41467-020-15954-x. Nat Commun. 2020. PMID: 32345962 Free PMC article.

7

Structural biology of telomeres and telomerase.

Smith EM, Pendlebury DF, Nandakumar J. Smith EM, et al. Among authors: pendlebury df. Cell Mol Life Sci. 2020 Jan;77(1):61-79. doi: 10.1007/s00018-019-03369-x. Epub 2019 Nov 14. Cell Mol Life Sci. 2020. PMID: 31728577 Free PMC article. Review.

8

Dysregulation of protein SUMOylation networks in Huntington's disease R6/2 mouse striatum.

Kachemov M, Vaibhav V, Smith C, Sundararaman N, Heath M, Pendlebury DF, Matlock A, Lau A, Morozko E, Lim RG, Reidling J, Steffan JS, Van Eyk JE, Thompson LM. Kachemov M, et al. Among authors: pendlebury df. Brain. 2024 Oct 11:awae319. doi: 10.1093/brain/awae319. Online ahead of print. Brain. 2024. PMID: 39391934

9

The TERB1 MYB domain suppresses telomere erosion in meiotic prophase I.

Zhang K, Tarczykowska A, Gupta DK, Pendlebury DF, Zuckerman C, Nandakumar J, Shibuya H. Zhang K, et al. Among authors: pendlebury df. Cell Rep. 2022 Jan 25;38(4):110289. doi: 10.1016/j.celrep.2021.110289. Cell Rep. 2022. PMID: 35081355 Free PMC article.

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