Martin EW - Search Results

1

Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and upon Multisite Phosphorylation.

Martin EW, Holehouse AS, Grace CR, Hughes A, Pappu RV, Mittag T. Martin EW, et al. J Am Chem Soc. 2016 Nov 30;138(47):15323-15335. doi: 10.1021/jacs.6b10272. Epub 2016 Nov 17. J Am Chem Soc. 2016. PMID: 27807972 Free PMC article.

2

A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.

Wang A, Conicella AE, Schmidt HB, Martin EW, Rhoads SN, Reeb AN, Nourse A, Ramirez Montero D, Ryan VH, Rohatgi R, Shewmaker F, Naik MT, Mittag T, Ayala YM, Fawzi NL. Wang A, et al. Among authors: martin ew. EMBO J. 2018 Mar 1;37(5):e97452. doi: 10.15252/embj.201797452. Epub 2018 Feb 9. EMBO J. 2018. PMID: 29438978 Free PMC article.

3

Relationship of Sequence and Phase Separation in Protein Low-Complexity Regions.

Martin EW, Mittag T. Martin EW, et al. Biochemistry. 2018 May 1;57(17):2478-2487. doi: 10.1021/acs.biochem.8b00008. Epub 2018 Mar 16. Biochemistry. 2018. PMID: 29517898 Free PMC article.

4

Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments.

Bouchard JJ, Otero JH, Scott DC, Szulc E, Martin EW, Sabri N, Granata D, Marzahn MR, Lindorff-Larsen K, Salvatella X, Schulman BA, Mittag T. Bouchard JJ, et al. Among authors: martin ew. Mol Cell. 2018 Oct 4;72(1):19-36.e8. doi: 10.1016/j.molcel.2018.08.027. Epub 2018 Sep 20. Mol Cell. 2018. PMID: 30244836 Free PMC article.

5

Dwelling at membranes promotes decisive signaling.

Martin EW, Mittag T. Martin EW, et al. Science. 2019 Mar 8;363(6431):1036-1037. doi: 10.1126/science.aaw6434. Science. 2019. PMID: 30846583 No abstract available.

6

Protein Network Structure Enables Switching between Liquid and Gel States.

Schmit JD, Bouchard JJ, Martin EW, Mittag T. Schmit JD, et al. Among authors: martin ew. J Am Chem Soc. 2020 Jan 15;142(2):874-883. doi: 10.1021/jacs.9b10066. Epub 2020 Jan 3. J Am Chem Soc. 2020. PMID: 31845799 Free PMC article.

7

Valence and patterning of aromatic residues determine the phase behavior of prion-like domains.

Martin EW, Holehouse AS, Peran I, Farag M, Incicco JJ, Bremer A, Grace CR, Soranno A, Pappu RV, Mittag T. Martin EW, et al. Science. 2020 Feb 7;367(6478):694-699. doi: 10.1126/science.aaw8653. Science. 2020. PMID: 32029630 Free PMC article.

8

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules.

Yang P, Mathieu C, Kolaitis RM, Zhang P, Messing J, Yurtsever U, Yang Z, Wu J, Li Y, Pan Q, Yu J, Martin EW, Mittag T, Kim HJ, Taylor JP. Yang P, et al. Among authors: martin ew. Cell. 2020 Apr 16;181(2):325-345.e28. doi: 10.1016/j.cell.2020.03.046. Cell. 2020. PMID: 32302571 Free PMC article.

9

Walking Along a Protein Phase Diagram to Determine Coexistence Points by Static Light Scattering.

Peran I, Martin EW, Mittag T. Peran I, et al. Among authors: martin ew. Methods Mol Biol. 2020;2141:715-730. doi: 10.1007/978-1-0716-0524-0_37. Methods Mol Biol. 2020. PMID: 32696386

10

Conformational Ensembles of an Intrinsically Disordered Protein Consistent with NMR, SAXS, and Single-Molecule FRET.

Gomes GW, Krzeminski M, Namini A, Martin EW, Mittag T, Head-Gordon T, Forman-Kay JD, Gradinaru CC. Gomes GW, et al. Among authors: martin ew. J Am Chem Soc. 2020 Sep 16;142(37):15697-15710. doi: 10.1021/jacs.0c02088. Epub 2020 Sep 4. J Am Chem Soc. 2020. PMID: 32840111 Free PMC article.

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