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Page 1
Proteome-scale Binary Interactomics in Human Cells.
Lievens S, Van der Heyden J, Masschaele D, De Ceuninck L, Petta I, Gupta S, De Puysseleyr V, Vauthier V, Lemmens I, De Clercq DJ, Defever D, Vanderroost N, De Smet AS, Eyckerman S, Van Calenbergh S, Martens L, De Bosscher K, Libert C, Hill DE, Vidal M, Tavernier J. Lievens S, et al. Among authors: vanderroost n. Mol Cell Proteomics. 2016 Dec;15(12):3624-3639. doi: 10.1074/mcp.M116.061994. Epub 2016 Nov 1. Mol Cell Proteomics. 2016. PMID: 27803151 Free PMC article.
Kinase Substrate Sensor (KISS), a mammalian in situ protein interaction sensor.
Lievens S, Gerlo S, Lemmens I, De Clercq DJ, Risseeuw MD, Vanderroost N, De Smet AS, Ruyssinck E, Chevet E, Van Calenbergh S, Tavernier J. Lievens S, et al. Among authors: vanderroost n. Mol Cell Proteomics. 2014 Dec;13(12):3332-42. doi: 10.1074/mcp.M114.041087. Epub 2014 Aug 25. Mol Cell Proteomics. 2014. PMID: 25154561 Free PMC article.
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation.
Sachse SM, Lievens S, Ribeiro LF, Dascenco D, Masschaele D, Horré K, Misbaer A, Vanderroost N, De Smet AS, Salta E, Erfurth ML, Kise Y, Nebel S, Van Delm W, Plaisance S, Tavernier J, De Strooper B, De Wit J, Schmucker D. Sachse SM, et al. Among authors: vanderroost n. EMBO J. 2019 Mar 15;38(6):e99669. doi: 10.15252/embj.201899669. Epub 2019 Feb 11. EMBO J. 2019. PMID: 30745319 Free PMC article.
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state.
Van Lint S, Van Parys A, Van Den Eeckhout B, Vandamme N, Plaisance S, Verhee A, Catteeuw D, Rogge E, De Geest J, Vanderroost N, Roels J, Saeys Y, Uzé G, Kley N, Cauwels A, Tavernier J. Van Lint S, et al. Among authors: vanderroost n. Mol Cancer. 2023 Nov 29;22(1):191. doi: 10.1186/s12943-023-01908-6. Mol Cancer. 2023. PMID: 38031106 Free PMC article.
Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies.
Huyghe L, Van Parys A, Cauwels A, Van Lint S, De Munter S, Bultinck J, Zabeau L, Hostens J, Goethals A, Vanderroost N, Verhee A, Uzé G, Kley N, Peelman F, Vandekerckhove B, Brouckaert P, Tavernier J. Huyghe L, et al. Among authors: vanderroost n. EMBO Mol Med. 2020 Feb 7;12(2):e11223. doi: 10.15252/emmm.201911223. Epub 2020 Jan 8. EMBO Mol Med. 2020. PMID: 31912630 Free PMC article.