Zhong YL - Search Results

1

Synthesis of the GPR40 Partial Agonist MK-8666 through a Kinetically Controlled Dynamic Enzymatic Ketone Reduction.

Hyde AM, Liu Z, Kosjek B, Tan L, Klapars A, Ashley ER, Zhong YL, Alvizo O, Agard NJ, Liu G, Gu X, Yasuda N, Limanto J, Huffman MA, Tschaen DM. Hyde AM, et al. Among authors: zhong yl. Org Lett. 2016 Nov 18;18(22):5888-5891. doi: 10.1021/acs.orglett.6b02910. Epub 2016 Nov 1. Org Lett. 2016. PMID: 27802043

2

Development of a practical, asymmetric synthesis of the hepatitis C virus protease inhibitor MK-5172.

Kuethe J, Zhong YL, Yasuda N, Beutner G, Linn K, Kim M, Marcune B, Dreher SD, Humphrey G, Pei T. Kuethe J, et al. Among authors: zhong yl. Org Lett. 2013 Aug 16;15(16):4174-7. doi: 10.1021/ol401864t. Epub 2013 Aug 6. Org Lett. 2013. PMID: 23919347

3

Practical and cost-effective manufacturing route for the synthesis of a β-lactamase inhibitor.

Miller SP, Zhong YL, Liu Z, Simeone M, Yasuda N, Limanto J, Chen Z, Lynch J, Capodanno V. Miller SP, et al. Among authors: zhong yl. Org Lett. 2014 Jan 3;16(1):174-7. doi: 10.1021/ol4031606. Epub 2013 Dec 13. Org Lett. 2014. PMID: 24329136

4

Unusual pyrimidine participation: efficient stereoselective synthesis of potent dual orexin receptor antagonist MK-6096.

Chung JY, Zhong YL, Maloney KM, Reamer RA, Moore JC, Strotman H, Kalinin A, Feng R, Strotman NA, Xiang B, Yasuda N. Chung JY, et al. Among authors: zhong yl. Org Lett. 2014 Nov 21;16(22):5890-3. doi: 10.1021/ol5028249. Epub 2014 Nov 3. Org Lett. 2014. PMID: 25365229

5

Process Chemistry in Antiviral Research.

Zhong YL, Yasuda N, Li H, McLaughlin M, Tschaen D. Zhong YL, et al. Top Curr Chem (Cham). 2016 Dec;374(6):77. doi: 10.1007/s41061-016-0076-5. Epub 2016 Nov 2. Top Curr Chem (Cham). 2016. PMID: 27807768 Review.

6

Synthesis of antifungal glucan synthase inhibitors from enfumafungin.

Zhong YL, Gauthier DR Jr, Shi YJ, McLaughlin M, Chung JY, Dagneau P, Marcune B, Krska SW, Ball RG, Reamer RA, Yasuda N. Zhong YL, et al. J Org Chem. 2012 Apr 6;77(7):3297-310. doi: 10.1021/jo300046v. Epub 2012 Mar 28. J Org Chem. 2012. PMID: 22423625

7

Asymmetric Synthesis of Functionalized trans-Cyclopropoxy Building Block for Grazoprevir.

Xu F, Zhong YL, Li H, Qi J, Desmond R, Song ZJ, Park J, Wang T, Truppo M, Humphrey GR, Ruck RT. Xu F, et al. Among authors: zhong yl. Org Lett. 2017 Nov 3;19(21):5880-5883. doi: 10.1021/acs.orglett.7b02867. Org Lett. 2017. PMID: 29052413

8

Catalytic asymmetric synthesis of an HIV integrase inhibitor.

Zhong YL, Krska SW, Zhou H, Reamer RA, Lee J, Sun Y, Askin D. Zhong YL, et al. Org Lett. 2009 Jan 15;11(2):369-72. doi: 10.1021/ol802604v. Org Lett. 2009. PMID: 19099496

9

A Concise and Atom-Economical Suzuki-Miyaura Coupling Reaction Using Unactivated Trialkyl- and Triarylboranes with Aryl Halides.

Li H, Zhong YL, Chen CY, Ferraro AE, Wang D. Li H, et al. Among authors: zhong yl. Org Lett. 2015 Jul 17;17(14):3616-9. doi: 10.1021/acs.orglett.5b01720. Epub 2015 Jun 30. Org Lett. 2015. PMID: 26125106

10

Practical synthesis of sultams via sulfonamide dianion alkylation: application to the synthesis of chiral sultams.

Lee J, Zhong YL, Reamer RA, Askin D. Lee J, et al. Among authors: zhong yl. Org Lett. 2003 Oct 30;5(22):4175-7. doi: 10.1021/ol0356183. Org Lett. 2003. PMID: 14572278

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