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Plasma succinate is a predictor of mortality in critically injured patients.
DʼAlessandro A, Moore HB, Moore EE, Reisz JA, Wither MJ, Ghasasbyan A, Chandler J, Silliman CC, Hansen KC, Banerjee A. DʼAlessandro A, et al. Among authors: wither mj. J Trauma Acute Care Surg. 2017 Sep;83(3):491-495. doi: 10.1097/TA.0000000000001565. J Trauma Acute Care Surg. 2017. PMID: 28590356 Free PMC article.
All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured patients.
Reisz JA, Wither MJ, Moore EE, Slaughter AL, Moore HB, Ghasabyan A, Chandler J, Schaub LJ, Fragoso M, Nunns G, Silliman CC, Hansen KC, Banerjee A, Sheppard FR, D'Alessandro A. Reisz JA, et al. Among authors: wither mj. J Trauma Acute Care Surg. 2018 Mar;84(3):537-541. doi: 10.1097/TA.0000000000001721. J Trauma Acute Care Surg. 2018. PMID: 29112093 Free PMC article.
Early hemorrhage triggers metabolic responses that build up during prolonged shock.
D'Alessandro A, Moore HB, Moore EE, Wither M, Nemkov T, Gonzalez E, Slaughter A, Fragoso M, Hansen KC, Silliman CC, Banerjee A. D'Alessandro A, et al. Am J Physiol Regul Integr Comp Physiol. 2015 Jun 15;308(12):R1034-44. doi: 10.1152/ajpregu.00030.2015. Epub 2015 Apr 15. Am J Physiol Regul Integr Comp Physiol. 2015. PMID: 25876652 Free PMC article.
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