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Page 1
Unified Software Solution for Efficient SPR Data Analysis in Drug Research.
Dahl G, Steigele S, Hillertz P, Tigerström A, Egnéus A, Mehrle A, Ginkel M, Edfeldt F, Holdgate G, O'Connell N, Kappler B, Brodte A, Rawlins PB, Davies G, Westberg EL, Folmer RH, Heyse S. Dahl G, et al. Among authors: edfeldt f. SLAS Discov. 2017 Feb;22(2):203-209. doi: 10.1177/1087057116675316. Epub 2016 Oct 28. SLAS Discov. 2017. PMID: 27789754 Free PMC article.
Fragment screening at AstraZeneca: developing the next generation biophysics fragment set.
Lucas SCC, Börjesson U, Bostock MJ, Cuff J, Edfeldt F, Embrey KJ, Eriksson PO, Gohlke A, Gunnarson A, Lainchbury M, Milbradt AG, Moore R, Rawlins PB, Sinclair I, Stubbs C, Storer RI. Lucas SCC, et al. Among authors: edfeldt f. RSC Med Chem. 2022 Jul 4;13(9):1052-1057. doi: 10.1039/d2md00154c. eCollection 2022 Sep 21. RSC Med Chem. 2022. PMID: 36324499 Free PMC article.
An improved model for fragment-based lead generation at AstraZeneca.
Fuller N, Spadola L, Cowen S, Patel J, Schönherr H, Cao Q, McKenzie A, Edfeldt F, Rabow A, Goodnow R. Fuller N, et al. Among authors: edfeldt f. Drug Discov Today. 2016 Aug;21(8):1272-83. doi: 10.1016/j.drudis.2016.04.023. Epub 2016 May 11. Drug Discov Today. 2016. PMID: 27179986 Review.
Interbase-FRET binding assay for pre-microRNAs.
Bood M, Del Nogal AW, Nilsson JR, Edfeldt F, Dahlén A, Lemurell M, Wilhelmsson LM, Grøtli M. Bood M, et al. Among authors: edfeldt f. Sci Rep. 2021 Apr 30;11(1):9396. doi: 10.1038/s41598-021-88922-0. Sci Rep. 2021. PMID: 33931703 Free PMC article.
HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase.
Evenäs J, Edfeldt F, Lepistö M, Svitacheva N, Synnergren A, Lundquist B, Gränse M, Rönnholm A, Varga M, Wright J, Wei M, Yue S, Wang J, Li C, Li X, Chen G, Liao Y, Lv G, Tjörnebo A, Narjes F. Evenäs J, et al. Among authors: edfeldt f. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1315-21. doi: 10.1016/j.bmcl.2014.01.050. Epub 2014 Jan 28. Bioorg Med Chem Lett. 2014. PMID: 24508129
15 results