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Unified Software Solution for Efficient SPR Data Analysis in Drug Research.
Dahl G, Steigele S, Hillertz P, Tigerström A, Egnéus A, Mehrle A, Ginkel M, Edfeldt F, Holdgate G, O'Connell N, Kappler B, Brodte A, Rawlins PB, Davies G, Westberg EL, Folmer RH, Heyse S. Dahl G, et al. Among authors: davies g. SLAS Discov. 2017 Feb;22(2):203-209. doi: 10.1177/1087057116675316. Epub 2016 Oct 28. SLAS Discov. 2017. PMID: 27789754 Free PMC article.
A High-Throughput Screening Triage Workflow to Authenticate a Novel Series of PFKFB3 Inhibitors.
St-Gallay SA, Bennett N, Critchlow SE, Curtis N, Davies G, Debreczeni J, Evans N, Hardern I, Holdgate G, Jones NP, Leach L, Maman S, McLoughlin S, Preston M, Rigoreau L, Thomas A, Turnbull AP, Walker G, Walsh J, Ward RA, Wheatley E, Winter-Holt J. St-Gallay SA, et al. Among authors: davies g. SLAS Discov. 2018 Jan;23(1):11-22. doi: 10.1177/2472555217732289. Epub 2017 Sep 25. SLAS Discov. 2018. PMID: 28945981 Free article.
High-Throughput Mechanism of Inhibition.
Davies G, Semple H, McCandless M, Cairns J, Holdgate GA. Davies G, et al. SLAS Discov. 2021 Feb;26(2):248-256. doi: 10.1177/2472555220983809. SLAS Discov. 2021. PMID: 33482076 Free article.
High throughput application of the NanoBiT Biochemical Assay for the discovery of selective inhibitors of the interaction of PI3K-p110α with KRAS.
Ismail M, Davies G, Sproat G, Monteverde T, Tart J, Acebrón-García-de-Eulate M, Gohlke A, Hancock D, Adhikari S, Stefanovic-Barrett S, Smith DM, Flemington V, Gleave-Hanford ES, Holdgate GA, Kettle JG, Downward J. Ismail M, et al. Among authors: davies g. SLAS Discov. 2024 Dec;29(8):100197. doi: 10.1016/j.slasd.2024.100197. Epub 2024 Nov 28. SLAS Discov. 2024. PMID: 39613028 Free article.
A perspective on the discovery of enzyme activators.
Turberville A, Semple H, Davies G, Ivanov D, Holdgate GA. Turberville A, et al. Among authors: davies g. SLAS Discov. 2022 Dec;27(8):419-427. doi: 10.1016/j.slasd.2022.09.001. Epub 2022 Sep 9. SLAS Discov. 2022. PMID: 36089246 Free article. Review.
3,578 results