Unciti-Broceta A - Search Results

1

Efficient Palladium-Triggered Release of Vorinostat from a Bioorthogonal Precursor.

Rubio-Ruiz B, Weiss JT, Unciti-Broceta A. Rubio-Ruiz B, et al. J Med Chem. 2016 Nov 10;59(21):9974-9980. doi: 10.1021/acs.jmedchem.6b01426. Epub 2016 Nov 2. J Med Chem. 2016. PMID: 27786474 Free article.

2

Tripod-like cationic lipids as novel gene carriers.

Unciti-Broceta A, Holder E, Jones LJ, Stevenson B, Turner AR, Porteous DJ, Boyd AC, Bradley M. Unciti-Broceta A, et al. J Med Chem. 2008 Jul 24;51(14):4076-84. doi: 10.1021/jm701493f. Epub 2008 Jun 26. J Med Chem. 2008. PMID: 18578515

3

Advancing cancer drug discovery towards more agile development of targeted combination therapies.

Carragher NO, Unciti-Broceta A, Cameron DA. Carragher NO, et al. Future Med Chem. 2012 Jan;4(1):87-105. doi: 10.4155/fmc.11.169. Future Med Chem. 2012. PMID: 22168166 Review.

4

Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach.

Weiss JT, Dawson JC, Macleod KG, Rybski W, Fraser C, Torres-Sánchez C, Patton EE, Bradley M, Carragher NO, Unciti-Broceta A. Weiss JT, et al. Nat Commun. 2014;5:3277. doi: 10.1038/ncomms4277. Nat Commun. 2014. PMID: 24522696 Free PMC article.

5

Development and bioorthogonal activation of palladium-labile prodrugs of gemcitabine.

Weiss JT, Dawson JC, Fraser C, Rybski W, Torres-Sánchez C, Bradley M, Patton EE, Carragher NO, Unciti-Broceta A. Weiss JT, et al. J Med Chem. 2014 Jun 26;57(12):5395-404. doi: 10.1021/jm500531z. Epub 2014 Jun 12. J Med Chem. 2014. PMID: 24867590 Free PMC article.

6

N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture.

Weiss JT, Fraser C, Rubio-Ruiz B, Myers SH, Crispin R, Dawson JC, Brunton VG, Patton EE, Carragher NO, Unciti-Broceta A. Weiss JT, et al. Front Chem. 2014 Jul 29;2:56. doi: 10.3389/fchem.2014.00056. eCollection 2014. Front Chem. 2014. PMID: 25121087 Free PMC article.

7

Palladium-mediated dealkylation of N-propargyl-floxuridine as a bioorthogonal oxygen-independent prodrug strategy.

Weiss JT, Carragher NO, Unciti-Broceta A. Weiss JT, et al. Sci Rep. 2015 Mar 19;5:9329. doi: 10.1038/srep09329. Sci Rep. 2015. PMID: 25788464 Free PMC article.

8

Bioorthogonal catalysis: Rise of the nanobots.

Unciti-Broceta A. Unciti-Broceta A. Nat Chem. 2015 Jul;7(7):538-9. doi: 10.1038/nchem.2291. Nat Chem. 2015. PMID: 26100798 No abstract available.

9

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective.

Myers SH, Brunton VG, Unciti-Broceta A. Myers SH, et al. J Med Chem. 2016 Apr 28;59(8):3593-608. doi: 10.1021/acs.jmedchem.5b01273. Epub 2015 Nov 20. J Med Chem. 2016. PMID: 26555154 Free article. Review.

10

Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase.

Fraser C, Dawson JC, Dowling R, Houston DR, Weiss JT, Munro AF, Muir M, Harrington L, Webster SP, Frame MC, Brunton VG, Patton EE, Carragher NO, Unciti-Broceta A. Fraser C, et al. J Med Chem. 2016 May 26;59(10):4697-710. doi: 10.1021/acs.jmedchem.6b00065. Epub 2016 May 4. J Med Chem. 2016. PMID: 27115835 Free PMC article.

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