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Pharmacokinetics and Metabolism of Selective Oxoeicosanoid (OXE) Receptor Antagonists and Their Effects on 5-Oxo-6,8,11,14-eicosatetraenoic Acid (5-Oxo-ETE)-Induced Granulocyte Activation in Monkeys.
Cossette C, Chourey S, Ye Q, Nagendra Reddy C, Gore V, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Cossette C, et al. Among authors: gravel s. J Med Chem. 2016 Nov 23;59(22):10127-10146. doi: 10.1021/acs.jmedchem.6b00895. Epub 2016 Nov 7. J Med Chem. 2016. PMID: 27766872
5-Oxo-ETE receptor antagonists.
Gore V, Patel P, Chang CT, Sivendran S, Kang N, Ouedraogo YP, Gravel S, Powell WS, Rokach J. Gore V, et al. Among authors: gravel s. J Med Chem. 2013 May 9;56(9):3725-32. doi: 10.1021/jm400480j. Epub 2013 Apr 26. J Med Chem. 2013. PMID: 23581530 Free PMC article.
Two Potent OXE-R Antagonists: Assignment of Stereochemistry.
Patel P, Reddy CN, Gore V, Chourey S, Ye Q, Ouedraogo YP, Gravel S, Powell WS, Rokach J. Patel P, et al. Among authors: gravel s. ACS Med Chem Lett. 2014 May 29;5(7):815-9. doi: 10.1021/ml500161v. eCollection 2014 Jul 10. ACS Med Chem Lett. 2014. PMID: 25050171 Free PMC article.
Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes.
Cossette C, Gravel S, Reddy CN, Gore V, Chourey S, Ye Q, Snyder NW, Mesaros CA, Blair IA, Lavoie JP, Reinero CR, Rokach J, Powell WS. Cossette C, et al. Among authors: gravel s. Biochem Pharmacol. 2015 Aug 1;96(3):247-55. doi: 10.1016/j.bcp.2015.05.009. Epub 2015 May 29. Biochem Pharmacol. 2015. PMID: 26032638 Free PMC article.
In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys.
Chourey S, Ye Q, Reddy CN, Cossette C, Gravel S, Zeller M, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Chourey S, et al. Among authors: gravel s. Biochem Pharmacol. 2017 Aug 15;138:107-118. doi: 10.1016/j.bcp.2017.04.031. Epub 2017 May 3. Biochem Pharmacol. 2017. PMID: 28476332 Free PMC article.
217 results