Smith JL - Search Results

1

Molecular pathogenesis of long QT syndrome type 2.

Smith JL, Anderson CL, Burgess DE, Elayi CS, January CT, Delisle BP. Smith JL, et al. J Arrhythm. 2016 Oct;32(5):373-380. doi: 10.1016/j.joa.2015.11.009. Epub 2016 Jan 22. J Arrhythm. 2016. PMID: 27761161 Free PMC article. Review.

2

Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER.

Smith JL, McBride CM, Nataraj PS, Bartos DC, January CT, Delisle BP. Smith JL, et al. Am J Physiol Cell Physiol. 2011 Jul;301(1):C75-85. doi: 10.1152/ajpcell.00494.2010. Epub 2011 Apr 13. Am J Physiol Cell Physiol. 2011. PMID: 21490315 Free PMC article.

3

Mechanistic basis for type 2 long QT syndrome caused by KCNH2 mutations that disrupt conserved arginine residues in the voltage sensor.

McBride CM, Smith AM, Smith JL, Reloj AR, Velasco EJ, Powell J, Elayi CS, Bartos DC, Burgess DE, Delisle BP. McBride CM, et al. Among authors: smith jl, smith am. J Membr Biol. 2013 May;246(5):355-64. doi: 10.1007/s00232-013-9539-6. Epub 2013 Apr 2. J Membr Biol. 2013. PMID: 23546015 Free PMC article.

4

Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum.

Smith JL, Reloj AR, Nataraj PS, Bartos DC, Schroder EA, Moss AJ, Ohno S, Horie M, Anderson CL, January CT, Delisle BP. Smith JL, et al. Am J Physiol Cell Physiol. 2013 Nov 1;305(9):C919-30. doi: 10.1152/ajpcell.00406.2012. Epub 2013 Jul 17. Am J Physiol Cell Physiol. 2013. PMID: 23864605 Free PMC article.

5

Functional Invalidation of Putative Sudden Infant Death Syndrome-Associated Variants in the KCNH2-Encoded Kv11.1 Channel.

Smith JL, Tester DJ, Hall AR, Burgess DE, Hsu CC, Elayi SC, Anderson CL, January CT, Luo JZ, Hartzel DN, Mirshahi UL, Murray MF, Mirshahi T, Ackerman MJ, Delisle BP. Smith JL, et al. Circ Arrhythm Electrophysiol. 2018 May;11(5):e005859. doi: 10.1161/CIRCEP.117.005859. Circ Arrhythm Electrophysiol. 2018. PMID: 29752375 Free PMC article.

6

Visualizing Mutation-Specific Differences in the Trafficking-Deficient Phenotype of Kv11.1 Proteins Linked to Long QT Syndrome Type 2.

Hall AR, Anderson CL, Smith JL, Mirshahi T, Elayi CS, January CT, Delisle BP. Hall AR, et al. Among authors: smith jl. Front Physiol. 2018 May 23;9:584. doi: 10.3389/fphys.2018.00584. eCollection 2018. Front Physiol. 2018. PMID: 29875689 Free PMC article.

7

The cardiomyocyte molecular clock regulates the circadian expression of Kcnh2 and contributes to ventricular repolarization.

Schroder EA, Burgess DE, Zhang X, Lefta M, Smith JL, Patwardhan A, Bartos DC, Elayi CS, Esser KA, Delisle BP. Schroder EA, et al. Among authors: smith jl. Heart Rhythm. 2015 Jun;12(6):1306-14. doi: 10.1016/j.hrthm.2015.02.019. Epub 2015 Feb 19. Heart Rhythm. 2015. PMID: 25701773 Free PMC article.

8

4-Hydroxynonenal disrupts zinc export in primary rat cortical cells.

Smith JL, Xiong S, Lovell MA. Smith JL, et al. Neurotoxicology. 2006 Jan;27(1):1-5. doi: 10.1016/j.neuro.2005.05.009. Epub 2005 Aug 24. Neurotoxicology. 2006. PMID: 16125244

9

The alpha1D-adrenergic receptor is expressed intracellularly and coupled to increases in intracellular calcium and reactive oxygen species in human aortic smooth muscle cells.

García-Cazarín ML, Smith JL, Olszewski KA, McCune DF, Simmerman LA, Hadley RW, Kraner SD, Piascik MT. García-Cazarín ML, et al. Among authors: smith jl. J Mol Signal. 2008 Feb 27;3:6. doi: 10.1186/1750-2187-3-6. J Mol Signal. 2008. PMID: 18304336 Free PMC article.

10

Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain.

Smith JL, Xiong S, Markesbery WR, Lovell MA. Smith JL, et al. Neuroscience. 2006 Jul 7;140(3):879-88. doi: 10.1016/j.neuroscience.2006.02.049. Epub 2006 Apr 3. Neuroscience. 2006. PMID: 16580781

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