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Adenosine Analog NITD008 Is a Potent Inhibitor of Zika Virus.
Deng YQ, Zhang NN, Li CF, Tian M, Hao JN, Xie XP, Shi PY, Qin CF. Deng YQ, et al. Among authors: shi py. Open Forum Infect Dis. 2016 Aug 30;3(4):ofw175. doi: 10.1093/ofid/ofw175. eCollection 2016 Oct. Open Forum Infect Dis. 2016. PMID: 27747251 Free PMC article.
A translation inhibitor that suppresses dengue virus in vitro and in vivo.
Wang QY, Kondreddi RR, Xie X, Rao R, Nilar S, Xu HY, Qing M, Chang D, Dong H, Yokokawa F, Lakshminarayana SB, Goh A, Schul W, Kramer L, Keller TH, Shi PY. Wang QY, et al. Among authors: shi py. Antimicrob Agents Chemother. 2011 Sep;55(9):4072-80. doi: 10.1128/AAC.00620-11. Epub 2011 Jul 5. Antimicrob Agents Chemother. 2011. PMID: 21730119 Free PMC article.
Inhibition of dengue virus by targeting viral NS4B protein.
Xie X, Wang QY, Xu HY, Qing M, Kramer L, Yuan Z, Shi PY. Xie X, et al. Among authors: shi py. J Virol. 2011 Nov;85(21):11183-95. doi: 10.1128/JVI.05468-11. Epub 2011 Aug 24. J Virol. 2011. PMID: 21865382 Free PMC article.
Rational design of a flavivirus vaccine by abolishing viral RNA 2'-O methylation.
Li SH, Dong H, Li XF, Xie X, Zhao H, Deng YQ, Wang XY, Ye Q, Zhu SY, Wang HJ, Zhang B, Leng QB, Zuest R, Qin ED, Qin CF, Shi PY. Li SH, et al. Among authors: shi py. J Virol. 2013 May;87(10):5812-9. doi: 10.1128/JVI.02806-12. Epub 2013 Mar 13. J Virol. 2013. PMID: 23487465 Free PMC article.
Rational design of a live attenuated dengue vaccine: 2'-o-methyltransferase mutants are highly attenuated and immunogenic in mice and macaques.
Züst R, Dong H, Li XF, Chang DC, Zhang B, Balakrishnan T, Toh YX, Jiang T, Li SH, Deng YQ, Ellis BR, Ellis EM, Poidinger M, Zolezzi F, Qin CF, Shi PY, Fink K. Züst R, et al. Among authors: shi py. PLoS Pathog. 2013;9(8):e1003521. doi: 10.1371/journal.ppat.1003521. Epub 2013 Aug 1. PLoS Pathog. 2013. PMID: 23935499 Free PMC article.
A chimeric dengue virus vaccine using Japanese encephalitis virus vaccine strain SA14-14-2 as backbone is immunogenic and protective against either parental virus in mice and nonhuman primates.
Li XF, Deng YQ, Yang HQ, Zhao H, Jiang T, Yu XD, Li SH, Ye Q, Zhu SY, Wang HJ, Zhang Y, Ma J, Yu YX, Liu ZY, Li YH, Qin ED, Shi PY, Qin CF. Li XF, et al. Among authors: shi py. J Virol. 2013 Dec;87(24):13694-705. doi: 10.1128/JVI.00931-13. Epub 2013 Oct 9. J Virol. 2013. PMID: 24109223 Free PMC article.
Dimerization of flavivirus NS4B protein.
Zou J, Xie X, Lee le T, Chandrasekaran R, Reynaud A, Yap L, Wang QY, Dong H, Kang C, Yuan Z, Lescar J, Shi PY. Zou J, et al. Among authors: shi py. J Virol. 2014 Mar;88(6):3379-91. doi: 10.1128/JVI.02782-13. Epub 2014 Jan 3. J Virol. 2014. PMID: 24390334 Free PMC article.
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