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TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction.
Rogers NM, Sharifi-Sanjani M, Yao M, Ghimire K, Bienes-Martinez R, Mutchler SM, Knupp HE, Baust J, Novelli EM, Ross M, St Croix C, Kutten JC, Czajka CA, Sembrat JC, Rojas M, Labrousse-Arias D, Bachman TN, Vanderpool RR, Zuckerbraun BS, Champion HC, Mora AL, Straub AC, Bilonick RA, Calzada MJ, Isenberg JS. Rogers NM, et al. Among authors: ghimire k. Cardiovasc Res. 2017 Jan;113(1):15-29. doi: 10.1093/cvr/cvw218. Epub 2016 Oct 13. Cardiovasc Res. 2017. PMID: 27742621 Free PMC article.
Nitric oxide: what's new to NO?
Ghimire K, Altmann HM, Straub AC, Isenberg JS. Ghimire K, et al. Am J Physiol Cell Physiol. 2017 Mar 1;312(3):C254-C262. doi: 10.1152/ajpcell.00315.2016. Epub 2016 Dec 14. Am J Physiol Cell Physiol. 2017. PMID: 27974299 Free PMC article. Review.
Deficiency in SIRP-α cytoplasmic recruitment confers protection from acute kidney injury.
Ghimire K, Chiba T, Minhas N, Meijles DN, Lu B, O'Connell P, Rogers NM. Ghimire K, et al. FASEB J. 2019 Oct;33(10):11528-11540. doi: 10.1096/fj.201900583R. Epub 2019 Aug 1. FASEB J. 2019. PMID: 31370677
These results identify parenchymal SIRP-alpha as an independent driver of IR-mediated AKI and a potential therapeutic target.-Ghimire, K., Chiba, T., Minhas, N., Meijles, D. N., Lu, B., O'Connell, P., Rogers, N. M. ...
These results identify parenchymal SIRP-alpha as an independent driver of IR-mediated AKI and a potential therapeutic target.-Ghimire
CD47 limits autophagy to promote acute kidney injury.
El-Rashid M, Ghimire K, Sanganeria B, Lu B, Rogers NM. El-Rashid M, et al. Among authors: ghimire k. FASEB J. 2019 Nov;33(11):12735-12749. doi: 10.1096/fj.201900120RR. Epub 2019 Aug 31. FASEB J. 2019. PMID: 31480863
These data suggest that activated CD47 promotes AKI through inhibition of autophagy and point to CD47 as a target to preserve renal function following injury.-El-Rashid, M., Ghimire, K., Sanganeria, B., Lu, B., Rogers, N. M. CD47 limits autophagy to promote acute ki …
These data suggest that activated CD47 promotes AKI through inhibition of autophagy and point to CD47 as a target to preserve renal function …
92 results