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Identification and characterization of the first small molecule inhibitor of MDMX.
Reed D, Shen Y, Shelat AA, Arnold LA, Ferreira AM, Zhu F, Mills N, Smithson DC, Regni CA, Bashford D, Cicero SA, Schulman BA, Jochemsen AG, Guy RK, Dyer MA. Reed D, et al. Among authors: guy rk. J Biol Chem. 2010 Apr 2;285(14):10786-96. doi: 10.1074/jbc.M109.056747. Epub 2010 Jan 15. J Biol Chem. 2010. PMID: 20080970 Free PMC article.
On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53.
Bista M, Smithson D, Pecak A, Salinas G, Pustelny K, Min J, Pirog A, Finch K, Zdzalik M, Waddell B, Wladyka B, Kedracka-Krok S, Dyer MA, Dubin G, Guy RK. Bista M, et al. Among authors: guy rk. PLoS One. 2012;7(6):e37518. doi: 10.1371/journal.pone.0037518. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675482 Free PMC article.
Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978.
Wang C, Zhao Q, Min J, Muniyan S, Vargas M, Wang X, Dong Y, Guy RK, Lin MF, Keiser J, Vennerstrom JL. Wang C, et al. Among authors: guy rk. Am J Trop Med Hyg. 2014 Jun;90(6):1156-8. doi: 10.4269/ajtmh.14-0029. Epub 2014 Mar 31. Am J Trop Med Hyg. 2014. PMID: 24686741 Free PMC article.
Organocatalytic, diastereo- and enantioselective synthesis of nonsymmetric cis-stilbene diamines: a platform for the preparation of single-enantiomer cis-imidazolines for protein-protein inhibition.
Vara BA, Mayasundari A, Tellis JC, Danneman MW, Arredondo V, Davis TA, Min J, Finch K, Guy RK, Johnston JN. Vara BA, et al. Among authors: guy rk. J Org Chem. 2014 Aug 1;79(15):6913-38. doi: 10.1021/jo501003r. Epub 2014 Jul 14. J Org Chem. 2014. PMID: 25017623 Free PMC article.
Potent Plasmodium falciparum gametocytocidal activity of diaminonaphthoquinones, lead antimalarial chemotypes identified in an antimalarial compound screen.
Tanaka TQ, Guiguemde WA, Barnett DS, Maron MI, Min J, Connelly MC, Suryadevara PK, Guy RK, Williamson KC. Tanaka TQ, et al. Among authors: guy rk. Antimicrob Agents Chemother. 2015 Mar;59(3):1389-97. doi: 10.1128/AAC.01930-13. Epub 2014 Dec 15. Antimicrob Agents Chemother. 2015. PMID: 25512421 Free PMC article.
8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction.
Pettersson M, Bliman D, Jacobsson J, Nilsson JR, Min J, Iconaru L, Guy RK, Kriwacki RW, Andréasson J, Grøtli M. Pettersson M, et al. Among authors: guy rk. PLoS One. 2015 May 5;10(5):e0124423. doi: 10.1371/journal.pone.0124423. eCollection 2015. PLoS One. 2015. PMID: 25942498 Free PMC article.
175 results