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Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.
Wang ZB, Jiang ZZ, Zhang QH, Hu MW, Huang L, Ou XH, Guo L, Ouyang YC, Hou Y, Brakebusch C, Schatten H, Sun QY. Wang ZB, et al. Among authors: guo l. Mol Biol Cell. 2013 Dec;24(24):3832-41. doi: 10.1091/mbc.E13-03-0123. Epub 2013 Oct 16. Mol Biol Cell. 2013. PMID: 24131996 Free PMC article.
Sperm-carried RNAs play critical roles in mouse embryonic development.
Guo L, Chao SB, Xiao L, Wang ZB, Meng TG, Li YY, Han ZM, Ouyang YC, Hou Y, Sun QY, Ou XH. Guo L, et al. Oncotarget. 2017 Jun 27;8(40):67394-67405. doi: 10.18632/oncotarget.18672. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978041 Free PMC article.
Mettl14 is required for mouse postimplantation development by facilitating epiblast maturation.
Meng TG, Lu X, Guo L, Hou GM, Ma XS, Li QN, Huang L, Fan LH, Zhao ZH, Ou XH, OuYang YC, Schatten H, Li L, Wang ZB, Sun QY. Meng TG, et al. Among authors: guo l. FASEB J. 2019 Jan;33(1):1179-1187. doi: 10.1096/fj.201800719R. Epub 2018 Aug 15. FASEB J. 2019. PMID: 30110177
Our data highlight the critical function of METTL14 as an m(6)A modification regulator in orchestrating early mouse embryogenesis.-Meng, T.-G., Lu, X., Guo, L., Hou, G.-M., Ma, X.-S., Li, Q.-N., Huang, L., Fan, L.-H., Zhao, Z.-H., Ou, X.-H., OuYang, Y. …
Our data highlight the critical function of METTL14 as an m(6)A modification regulator in orchestrating early mouse embryogenesis.-Meng, T.- …
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