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Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects.
Green JA, Mohamed K, Goyal N, Bouhired S, Hussaini A, Jones SW, Koh GC, Kostov I, Taylor M, Wolstenholm A, Duparc S. Green JA, et al. Among authors: koh gc. Antimicrob Agents Chemother. 2016 Nov 21;60(12):7321-7332. doi: 10.1128/AAC.01588-16. Print 2016 Dec. Antimicrob Agents Chemother. 2016. PMID: 27697758 Free PMC article. Clinical Trial.
Tafenoquine treatment of Plasmodium vivax malaria: suggestive evidence that CYP2D6 reduced metabolism is not associated with relapse in the Phase 2b DETECTIVE trial.
St Jean PL, Xue Z, Carter N, Koh GC, Duparc S, Taylor M, Beaumont C, Llanos-Cuentas A, Rueangweerayut R, Krudsood S, Green JA, Rubio JP. St Jean PL, et al. Among authors: koh gc. Malar J. 2016 Feb 18;15:97. doi: 10.1186/s12936-016-1145-5. Malar J. 2016. PMID: 26888075 Free PMC article. Clinical Trial.
A human microdose study of the antimalarial drug GSK3191607 in healthy volunteers.
Okour M, Derimanov G, Barnett R, Fernandez E, Ferrer S, Gresham S, Hossain M, Gamo FJ, Koh G, Pereira A, Rolfe K, Wong D, Young G, Rami H, Haselden J. Okour M, et al. Br J Clin Pharmacol. 2018 Mar;84(3):482-489. doi: 10.1111/bcp.13476. Epub 2017 Dec 29. Br J Clin Pharmacol. 2018. PMID: 29168205 Free PMC article. Clinical Trial.
Population Pharmacokinetics of Tafenoquine, a Novel Antimalarial.
Thakkar N, Green JA, Koh GCKW, Duparc S, Tenero D, Goyal N. Thakkar N, et al. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e00711-18. doi: 10.1128/AAC.00711-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30201820 Free PMC article.
Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria.
Lacerda MVG, Llanos-Cuentas A, Krudsood S, Lon C, Saunders DL, Mohammed R, Yilma D, Batista Pereira D, Espino FEJ, Mia RZ, Chuquiyauri R, Val F, Casapía M, Monteiro WM, Brito MAM, Costa MRF, Buathong N, Noedl H, Diro E, Getie S, Wubie KM, Abdissa A, Zeynudin A, Abebe C, Tada MS, Brand F, Beck HP, Angus B, Duparc S, Kleim JP, Kellam LM, Rousell VM, Jones SW, Hardaker E, Mohamed K, Clover DD, Fletcher K, Breton JJ, Ugwuegbulam CO, Green JA, Koh GCKW. Lacerda MVG, et al. N Engl J Med. 2019 Jan 17;380(3):215-228. doi: 10.1056/NEJMoa1710775. N Engl J Med. 2019. PMID: 30650322 Free PMC article. Clinical Trial.
Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria.
Llanos-Cuentas A, Lacerda MVG, Hien TT, Vélez ID, Namaik-Larp C, Chu CS, Villegas MF, Val F, Monteiro WM, Brito MAM, Costa MRF, Chuquiyauri R, Casapía M, Nguyen CH, Aruachan S, Papwijitsil R, Nosten FH, Bancone G, Angus B, Duparc S, Craig G, Rousell VM, Jones SW, Hardaker E, Clover DD, Kendall L, Mohamed K, Koh GCKW, Wilches VM, Breton JJ, Green JA. Llanos-Cuentas A, et al. N Engl J Med. 2019 Jan 17;380(3):229-241. doi: 10.1056/NEJMoa1802537. N Engl J Med. 2019. PMID: 30650326 Free PMC article. Clinical Trial.
Randomized Placebo-Controlled Trial Evaluating the Ophthalmic Safety of Single-Dose Tafenoquine in Healthy Volunteers.
Ackert J, Mohamed K, Slakter JS, El-Harazi S, Berni A, Gevorkyan H, Hardaker E, Hussaini A, Jones SW, Koh GCKW, Patel J, Rasmussen S, Kelly DS, Barañano DE, Thompson JT, Warren KA, Sergott RC, Tonkyn J, Wolstenholme A, Coleman H, Yuan A, Duparc S, Green JA. Ackert J, et al. Drug Saf. 2019 Sep;42(9):1103-1114. doi: 10.1007/s40264-019-00839-w. Drug Saf. 2019. PMID: 31187437 Free PMC article. Clinical Trial.
253 results