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Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM.
Cell Death Differ. 2016 Dec;23(12):2054-2062. doi: 10.1038/cdd.2016.96. Epub 2016 Sep 30.
Cell Death Differ. 2016.
PMID: 27689874
Free PMC article.
Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein.
Herold MJ, Rohrbeck L, Lang MJ, Grumont R, Gerondakis S, Tai L, Bouillet P, Kaufmann T, Strasser A.
Herold MJ, et al. Among authors: rohrbeck l.
EMBO Rep. 2013 Nov;14(11):992-8. doi: 10.1038/embor.2013.152. Epub 2013 Sep 24.
EMBO Rep. 2013.
PMID: 24060902
Free PMC article.
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BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival.
Lee EF, Harris TJ, Tran S, Evangelista M, Arulananda S, John T, Ramnac C, Hobbs C, Zhu H, Gunasingh G, Segal D, Behren A, Cebon J, Dobrovic A, Mariadason JM, Strasser A, Rohrbeck L, Haass NK, Herold MJ, Fairlie WD.
Lee EF, et al. Among authors: rohrbeck l.
Cell Death Dis. 2019 Apr 24;10(5):342. doi: 10.1038/s41419-019-1568-3.
Cell Death Dis. 2019.
PMID: 31019203
Free PMC article.
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Pro-apoptotic BIM is an essential initiator of physiological endothelial cell death independent of regulation by FOXO3.
Koenig MN, Naik E, Rohrbeck L, Herold MJ, Trounson E, Bouillet P, Thomas T, Voss AK, Strasser A, Coultas L.
Koenig MN, et al. Among authors: rohrbeck l.
Cell Death Differ. 2014 Nov;21(11):1687-95. doi: 10.1038/cdd.2014.90. Epub 2014 Jun 27.
Cell Death Differ. 2014.
PMID: 24971484
Free PMC article.
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Hoxb8 regulates expression of microRNAs to control cell death and differentiation.
Salmanidis M, Brumatti G, Narayan N, Green BD, van den Bergen JA, Sandow JJ, Bert AG, Silke N, Sladic R, Puthalakath H, Rohrbeck L, Okamoto T, Bouillet P, Herold MJ, Goodall GJ, Jabbour AM, Ekert PG.
Salmanidis M, et al. Among authors: rohrbeck l.
Cell Death Differ. 2013 Oct;20(10):1370-80. doi: 10.1038/cdd.2013.92. Epub 2013 Jul 19.
Cell Death Differ. 2013.
PMID: 23872792
Free PMC article.
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Spontaneous retrotransposon insertion into TNF 3'UTR causes heart valve disease and chronic polyarthritis.
Lacey D, Hickey P, Arhatari BD, O'Reilly LA, Rohrbeck L, Kiriazis H, Du XJ, Bouillet P.
Lacey D, et al. Among authors: rohrbeck l.
Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9698-703. doi: 10.1073/pnas.1508399112. Epub 2015 Jul 20.
Proc Natl Acad Sci U S A. 2015.
PMID: 26195802
Free PMC article.
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GPR43 regulates marginal zone B-cell responses to foreign and endogenous antigens.
Rohrbeck L, Adori M, Wang S, He C, Tibbitt CA, Chernyshev M, Sirel M, Ribacke U, Murrell B, Bohlooly-Y M, Karlsson MC, Karlsson Hedestam GB, Coquet JM.
Rohrbeck L, et al.
Immunol Cell Biol. 2021 Feb;99(2):234-243. doi: 10.1111/imcb.12399. Epub 2020 Sep 28.
Immunol Cell Biol. 2021.
PMID: 32888232
Free PMC article.
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PPAR-γ promotes type 2 immune responses in allergy and nematode infection.
Chen T, Tibbitt CA, Feng X, Stark JM, Rohrbeck L, Rausch L, Sedimbi SK, Karlsson MCI, Lambrecht BN, Karlsson Hedestam GB, Hendriks RW, Chambers BJ, Nylén S, Coquet JM.
Chen T, et al. Among authors: rohrbeck l.
Sci Immunol. 2017 Mar 10;2(9):eaal5196. doi: 10.1126/sciimmunol.aal5196.
Sci Immunol. 2017.
PMID: 28783701
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