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The PI3K/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma.
Chatterjee M, Andrulis M, Stühmer T, Müller E, Hofmann C, Steinbrunn T, Heimberger T, Schraud H, Kressmann S, Einsele H, Bargou RC. Chatterjee M, et al. Among authors: steinbrunn t. Haematologica. 2013 Jul;98(7):1132-41. doi: 10.3324/haematol.2012.066175. Epub 2012 Oct 12. Haematologica. 2013. PMID: 23065523 Free PMC article.
PI3K-dependent multiple myeloma cell survival is mediated by the PIK3CA isoform.
Hofmann C, Stühmer T, Schmiedl N, Wetzker R, Mottok A, Rosenwald A, Langer C, Zovko J, Chatterjee M, Einsele H, Bargou RC, Steinbrunn T. Hofmann C, et al. Among authors: steinbrunn t. Br J Haematol. 2014 Aug;166(4):529-39. doi: 10.1111/bjh.12920. Epub 2014 Apr 26. Br J Haematol. 2014. PMID: 24766330 Free article.
RAL GTPases mediate multiple myeloma cell survival and are activated independently of oncogenic RAS.
Seibold M, Stühmer T, Kremer N, Mottok A, Scholz CJ, Schlosser A, Leich E, Holzgrabe U, Brünnert D, Barrio S, Kortüm MK, Solimando AG, Chatterjee M, Einsele H, Rosenwald A, Bargou RC, Steinbrunn T. Seibold M, et al. Among authors: steinbrunn t. Haematologica. 2020 Sep 1;105(9):2316-2326. doi: 10.3324/haematol.2019.223024. Haematologica. 2020. PMID: 33054056 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 31601693
Novel molecular subgroups within the context of receptor tyrosine kinase and adhesion signalling in multiple myeloma.
Leich E, Schreder M, Pischimarov J, Stühmer T, Steinbrunn T, Rudelius M, Brünnert D, Chatterjee M, Langer C, Keppler S, Heredia-Guerrero SC, Einsele H, Knop S, Bargou RC, Rosenwald A. Leich E, et al. Among authors: steinbrunn t. Blood Cancer J. 2021 Mar 4;11(3):51. doi: 10.1038/s41408-021-00442-2. Blood Cancer J. 2021. PMID: 33664224 Free PMC article. No abstract available.
25 results