Ghadessy F - Search Results

1

Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens.

Siau JW, Coffill CR, Zhang WV, Tan YS, Hundt J, Lane D, Verma C, Ghadessy F. Siau JW, et al. Among authors: ghadessy f. Sci Rep. 2016 Sep 28;6:33972. doi: 10.1038/srep33972. Sci Rep. 2016. PMID: 27678309 Free PMC article.

2

Directed evolution of p53 variants with altered DNA-binding specificities by in vitro compartmentalization.

Fen CX, Coomber DW, Lane DP, Ghadessy FJ. Fen CX, et al. J Mol Biol. 2007 Aug 31;371(5):1238-48. doi: 10.1016/j.jmb.2007.05.099. Epub 2007 Jun 9. J Mol Biol. 2007. PMID: 17610896

3

Mdm2 and p53 are highly conserved from placozoans to man.

Lane DP, Cheok CF, Brown C, Madhumalar A, Ghadessy FJ, Verma C. Lane DP, et al. Cell Cycle. 2010 Feb 1;9(3):540-7. doi: 10.4161/cc.9.3.10516. Cell Cycle. 2010. PMID: 20081368

4

The Mdm2 and p53 genes are conserved in the Arachnids.

Lane DP, Cheok CF, Brown CJ, Madhumalar A, Ghadessy FJ, Verma C. Lane DP, et al. Cell Cycle. 2010 Feb 15;9(4):748-54. doi: 10.4161/cc.9.4.10616. Epub 2010 Feb 12. Cell Cycle. 2010. PMID: 20160485

5

Detection of the 113p53 protein isoform: a p53-induced protein that feeds back on the p53 pathway to modulate the p53 response in zebrafish.

Guo L, Chua J, Vijayakumar D, Lee KC, Lim K, Eng H, Ghadessy F, Coomber D, Lane DP. Guo L, et al. Among authors: ghadessy f. Cell Cycle. 2010 May 15;9(10):1998-2007. doi: 10.4161/cc.9.10.11732. Epub 2010 May 15. Cell Cycle. 2010. PMID: 20505327

6

Development of a novel multiplex in vitro binding assay to profile p53-DNA interactions.

Goh W, Lane D, Ghadessy F. Goh W, et al. Among authors: ghadessy f. Cell Cycle. 2010 Aug 1;9(15):3030-8. doi: 10.4161/cc.9.15.12436. Cell Cycle. 2010. PMID: 20714218

7

Analysis of p53 binding to DNA by fluorescence imaging microscopy.

Ong HJ, Siau JW, Zhang JB, Hong M, Flotow H, Ghadessy F. Ong HJ, et al. Among authors: ghadessy f. Micron. 2012 Sep;43(9):996-1000. doi: 10.1016/j.micron.2012.03.024. Epub 2012 Apr 6. Micron. 2012. PMID: 22537717

8

Binding of Translationally Controlled Tumour Protein to the N-terminal domain of HDM2 is inhibited by nutlin-3.

Funston G, Goh W, Wei SJ, Tng QS, Brown C, Jiah Tong L, Verma C, Lane D, Ghadessy F. Funston G, et al. Among authors: ghadessy f. PLoS One. 2012;7(8):e42642. doi: 10.1371/journal.pone.0042642. Epub 2012 Aug 13. PLoS One. 2012. PMID: 22912717 Free PMC article.

9

A generic scaffold for conversion of peptide ligands into homogenous biosensors.

Nirantar SR, Yeo KS, Chee S, Lane DP, Ghadessy FJ. Nirantar SR, et al. Biosens Bioelectron. 2013 Sep 15;47:421-8. doi: 10.1016/j.bios.2013.03.049. Epub 2013 Mar 29. Biosens Bioelectron. 2013. PMID: 23612064

10

In vitro selection of mutant HDM2 resistant to Nutlin inhibition.

Wei SJ, Joseph T, Sim AY, Yurlova L, Zolghadr K, Lane D, Verma C, Ghadessy F. Wei SJ, et al. Among authors: ghadessy f. PLoS One. 2013 Apr 30;8(4):e62564. doi: 10.1371/journal.pone.0062564. Print 2013. PLoS One. 2013. PMID: 23653682 Free PMC article.

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