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Vaccination with a genetically modified Brugia malayi cysteine protease inhibitor-2 reduces adult parasite numbers and affects the fertility of female worms following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae.
Arumugam S, Wei J, Ward D, Abraham D, Lustigman S, Zhan B, Klei TR. Arumugam S, et al. Among authors: wei j. Int J Parasitol. 2014 Sep;44(10):675-9. doi: 10.1016/j.ijpara.2014.05.003. Epub 2014 Jun 12. Int J Parasitol. 2014. PMID: 24929131 Free PMC article.
Expression, purification, immunogenicity, and protective efficacy of a recombinant Tc24 antigen as a vaccine against Trypanosoma cruzi infection in mice.
Martinez-Campos V, Martinez-Vega P, Ramirez-Sierra MJ, Rosado-Vallado M, Seid CA, Hudspeth EM, Wei J, Liu Z, Kwityn C, Hammond M, Ortega-López J, Zhan B, Hotez PJ, Bottazzi ME, Dumonteil E. Martinez-Campos V, et al. Among authors: wei j. Vaccine. 2015 Aug 26;33(36):4505-12. doi: 10.1016/j.vaccine.2015.07.017. Epub 2015 Jul 17. Vaccine. 2015. PMID: 26192358
Expression and purification of an engineered, yeast-expressed Leishmania donovani nucleoside hydrolase with immunogenic properties.
Hudspeth EM, Wang Q, Seid CA, Hammond M, Wei J, Liu Z, Zhan B, Pollet J, Heffernan MJ, McAtee CP, Engler DA, Matsunami RK, Strych U, Asojo OA, Hotez PJ, Bottazzi ME. Hudspeth EM, et al. Among authors: wei j. Hum Vaccin Immunother. 2016 Jul 2;12(7):1707-20. doi: 10.1080/21645515.2016.1139254. Epub 2016 Feb 2. Hum Vaccin Immunother. 2016. PMID: 26839079 Free PMC article.
Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection.
Arumugam S, Wei J, Liu Z, Abraham D, Bell A, Bottazzi ME, Hotez PJ, Zhan B, Lustigman S, Klei TR. Arumugam S, et al. Among authors: wei j. PLoS Negl Trop Dis. 2016 Apr 5;10(4):e0004586. doi: 10.1371/journal.pntd.0004586. eCollection 2016 Apr. PLoS Negl Trop Dis. 2016. PMID: 27045170 Free PMC article.
Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease.
Seid CA, Jones KM, Pollet J, Keegan B, Hudspeth E, Hammond M, Wei J, McAtee CP, Versteeg L, Gutierrez A, Liu Z, Zhan B, Respress JL, Strych U, Bottazzi ME, Hotez PJ. Seid CA, et al. Among authors: wei j. Hum Vaccin Immunother. 2017 Mar 4;13(3):621-633. doi: 10.1080/21645515.2016.1242540. Epub 2016 Oct 13. Hum Vaccin Immunother. 2017. PMID: 27737611 Free PMC article.
Expression, purification, immunogenicity and protective efficacy of a recombinant nucleoside hydrolase from Leishmania donovani, a vaccine candidate for preventing cutaneous leishmaniasis.
McAtee CP, Seid CA, Hammond M, Hudspeth E, Keegan BP, Liu Z, Wei J, Zhan B, Arjona-Sabido R, Cruz-Chan V, Dumonteil E, Hotez PJ, Bottazzi ME. McAtee CP, et al. Among authors: wei j. Protein Expr Purif. 2017 Feb;130:129-136. doi: 10.1016/j.pep.2016.10.008. Epub 2016 Oct 20. Protein Expr Purif. 2017. PMID: 27773761
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