Vangala JR - Search Results

1

Nrf1 can be processed and activated in a proteasome-independent manner.

Vangala JR, Sotzny F, Krüger E, Deshaies RJ, Radhakrishnan SK. Vangala JR, et al. Curr Biol. 2016 Sep 26;26(18):R834-R835. doi: 10.1016/j.cub.2016.08.008. Curr Biol. 2016. PMID: 27676297 Free PMC article.

2

Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex.

Vangala JR, Radhakrishnan SK. Vangala JR, et al. J Biol Chem. 2019 Feb 8;294(6):2036-2045. doi: 10.1074/jbc.RA118.006290. Epub 2018 Dec 17. J Biol Chem. 2019. PMID: 30559296 Free PMC article.

3

Disabling the Protease DDI2 Attenuates the Transcriptional Activity of NRF1 and Potentiates Proteasome Inhibitor Cytotoxicity.

Northrop A, Vangala JR, Feygin A, Radhakrishnan SK. Northrop A, et al. Among authors: vangala jr. Int J Mol Sci. 2020 Jan 3;21(1):327. doi: 10.3390/ijms21010327. Int J Mol Sci. 2020. PMID: 31947743 Free PMC article.

4

Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.

Tomlin FM, Gerling-Driessen UIM, Liu YC, Flynn RA, Vangala JR, Lentz CS, Clauder-Muenster S, Jakob P, Mueller WF, Ordoñez-Rueda D, Paulsen M, Matsui N, Foley D, Rafalko A, Suzuki T, Bogyo M, Steinmetz LM, Radhakrishnan SK, Bertozzi CR. Tomlin FM, et al. Among authors: vangala jr. ACS Cent Sci. 2017 Nov 22;3(11):1143-1155. doi: 10.1021/acscentsci.7b00224. Epub 2017 Oct 25. ACS Cent Sci. 2017. PMID: 29202016 Free PMC article.

5

BET Inhibitors Synergize with Carfilzomib to Induce Cell Death in Cancer Cells via Impairing Nrf1 Transcriptional Activity and Exacerbating the Unfolded Protein Response.

Vangala JR, Potluri A, Radhakrishnan SK. Vangala JR, et al. Biomolecules. 2020 Mar 26;10(4):501. doi: 10.3390/biom10040501. Biomolecules. 2020. PMID: 32224969 Free PMC article.

6

Regulation of PSMB5 protein and β subunits of mammalian proteasome by constitutively activated signal transducer and activator of transcription 3 (STAT3): potential role in bortezomib-mediated anticancer therapy.

Vangala JR, Dudem S, Jain N, Kalivendi SV. Vangala JR, et al. J Biol Chem. 2014 May 2;289(18):12612-22. doi: 10.1074/jbc.M113.542829. Epub 2014 Mar 13. J Biol Chem. 2014. PMID: 24627483 Free PMC article.

7

Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents.

Reddy MA, Jain N, Yada D, Kishore C, Vangala JR, P Surendra R, Addlagatta A, Kalivendi SV, Sreedhar B. Reddy MA, et al. Among authors: vangala jr. J Med Chem. 2011 Oct 13;54(19):6751-60. doi: 10.1021/jm200639r. Epub 2011 Sep 2. J Med Chem. 2011. PMID: 21851083

8

Stereoselective total synthesis of (+)-oploxyne A, (-)-oploxyne B, and their C-10 epimers and structure revision of natural oploxyne B.

Yadav JS, Boyapelly K, Alugubelli SR, Pabbaraja S, Vangala JR, Kalivendi SV. Yadav JS, et al. Among authors: vangala jr. J Org Chem. 2011 Apr 15;76(8):2568-76. doi: 10.1021/jo102445h. Epub 2011 Mar 17. J Org Chem. 2011. PMID: 21413759

9

Two new sesquiterpenoids from the rhizomes of Nardostachys jatamansi.

Rekha K, Rao RR, Pandey R, Prasad KR, Babu KS, Vangala JR, Kalivendi SV, Rao JM. Rekha K, et al. Among authors: vangala jr. J Asian Nat Prod Res. 2013;15(2):111-6. doi: 10.1080/10286020.2012.738673. J Asian Nat Prod Res. 2013. PMID: 23431964

10

Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy.

Ward MA, Vangala JR, Kamber Kaya HE, Byers HA, Hosseini N, Diaz A, Cuervo AM, Kaushik S, Radhakrishnan SK. Ward MA, et al. Among authors: vangala jr. J Cell Biol. 2024 Jun 3;223(6):e202306150. doi: 10.1083/jcb.202306150. Epub 2024 Apr 24. J Cell Biol. 2024. PMID: 38656405 Free PMC article.

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