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A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in vitro.
Blaschke M, McKinnon R, Nguyen CH, Holzner S, Zehl M, Atanasov AG, Schelch K, Krieger S, Diaz R, Frisch R, Feistel B, Jäger W, Ecker GF, Dirsch VM, Grusch M, Zupko I, Urban E, Kopp B, Krupitza G. Blaschke M, et al. Among authors: zehl m. Mutat Res. 2015 Jul;777:79-90. doi: 10.1016/j.mrfmmm.2015.04.011. Epub 2015 May 5. Mutat Res. 2015. PMID: 25989051
Resveratrol Inhibits Key Steps of Steroid Metabolism in a Human Estrogen-Receptor Positive Breast Cancer Model: Impact on Cellular Proliferation.
Poschner S, Maier-Salamon A, Zehl M, Wackerlig J, Dobusch D, Meshcheryakova A, Mechtcheriakova D, Thalhammer T, Pachmann B, Jäger W. Poschner S, et al. Among authors: zehl m. Front Pharmacol. 2018 Jul 10;9:742. doi: 10.3389/fphar.2018.00742. eCollection 2018. Front Pharmacol. 2018. PMID: 30042681 Free PMC article.
104 results