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Page 1
Discovery of novel 2',4'-dimethyl-[4,5'-bithiazol]-2-yl amino derivatives as orally bioavailable TRPV4 antagonists for the treatment of pain: Part 1.
Tsuno N, Yukimasa A, Yoshida O, Ichihashi Y, Inoue T, Ueno T, Yamaguchi H, Matsuda H, Funaki S, Yamanada N, Tanimura M, Nagamatsu D, Nishimura Y, Ito T, Soga M, Horita N, Yamamoto M, Hinata M, Imai M, Morioka Y, Kanemasa T, Sakaguchi G, Iso Y. Tsuno N, et al. Among authors: yamanada n. Bioorg Med Chem Lett. 2016 Oct 15;26(20):4930-4935. doi: 10.1016/j.bmcl.2016.09.013. Epub 2016 Sep 7. Bioorg Med Chem Lett. 2016. PMID: 27637151
Pharmacological evaluation of novel (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives as TRPV4 antagonists for the treatment of pain.
Tsuno N, Yukimasa A, Yoshida O, Suzuki S, Nakai H, Ogawa T, Fujiu M, Takaya K, Nozu A, Yamaguchi H, Matsuda H, Funaki S, Yamanada N, Tanimura M, Nagamatsu D, Asaki T, Horita N, Yamamoto M, Hinata M, Soga M, Imai M, Morioka Y, Kanemasa T, Sakaguchi G, Iso Y. Tsuno N, et al. Among authors: yamanada n. Bioorg Med Chem. 2017 Apr 1;25(7):2177-2190. doi: 10.1016/j.bmc.2017.02.047. Epub 2017 Mar 1. Bioorg Med Chem. 2017. PMID: 28284871
Organelle-targeted delivery of biological macromolecules using the protein transduction domain: potential applications for Peptide aptamer delivery into the nucleus.
Yoshikawa T, Sugita T, Mukai Y, Yamanada N, Nagano K, Nabeshi H, Yoshioka Y, Nakagawa S, Abe Y, Kamada H, Tsunoda S, Tsutsumi Y. Yoshikawa T, et al. Among authors: yamanada n. J Mol Biol. 2008 Jul 25;380(5):777-82. doi: 10.1016/j.jmb.2008.05.047. Epub 2008 May 29. J Mol Biol. 2008. PMID: 18571668
Comparative study on transduction and toxicity of protein transduction domains.
Sugita T, Yoshikawa T, Mukai Y, Yamanada N, Imai S, Nagano K, Yoshida Y, Shibata H, Yoshioka Y, Nakagawa S, Kamada H, Tsunoda SI, Tsutsumi Y. Sugita T, et al. Among authors: yamanada n. Br J Pharmacol. 2008 Mar;153(6):1143-52. doi: 10.1038/sj.bjp.0707678. Epub 2008 Jan 28. Br J Pharmacol. 2008. PMID: 18223668 Free PMC article.
Improved cytosolic translocation and tumor-killing activity of Tat-shepherdin conjugates mediated by co-treatment with Tat-fused endosome-disruptive HA2 peptide.
Sugita T, Yoshikawa T, Mukai Y, Yamanada N, Imai S, Nagano K, Yoshida Y, Shibata H, Yoshioka Y, Nakagawa S, Kamada H, Tsunoda S, Tsutsumi Y. Sugita T, et al. Among authors: yamanada n. Biochem Biophys Res Commun. 2007 Nov 30;363(4):1027-32. doi: 10.1016/j.bbrc.2007.09.077. Epub 2007 Sep 29. Biochem Biophys Res Commun. 2007. PMID: 17923117