Neale G - Search Results

1

mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.

Zeng H, Cohen S, Guy C, Shrestha S, Neale G, Brown SA, Cloer C, Kishton RJ, Gao X, Youngblood B, Do M, Li MO, Locasale JW, Rathmell JC, Chi H. Zeng H, et al. Among authors: neale g. Immunity. 2016 Sep 20;45(3):540-554. doi: 10.1016/j.immuni.2016.08.017. Epub 2016 Sep 13. Immunity. 2016. PMID: 27637146 Free PMC article.

2

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.

Shi LZ, Wang R, Huang G, Vogel P, Neale G, Green DR, Chi H. Shi LZ, et al. Among authors: neale g. J Exp Med. 2011 Jul 4;208(7):1367-76. doi: 10.1084/jem.20110278. Epub 2011 Jun 27. J Exp Med. 2011. PMID: 21708926 Free PMC article.

3

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.

Yang K, Neale G, Green DR, He W, Chi H. Yang K, et al. Among authors: neale g. Nat Immunol. 2011 Jul 17;12(9):888-97. doi: 10.1038/ni.2068. Nat Immunol. 2011. PMID: 21765414 Free PMC article.

4

Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.

Wang Y, Huang G, Vogel P, Neale G, Reizis B, Chi H. Wang Y, et al. Among authors: neale g. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):E343-52. doi: 10.1073/pnas.1115635109. Epub 2012 Jan 23. Proc Natl Acad Sci U S A. 2012. PMID: 22308391 Free PMC article.

5

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.

Zeng H, Yang K, Cloer C, Neale G, Vogel P, Chi H. Zeng H, et al. Among authors: neale g. Nature. 2013 Jul 25;499(7459):485-90. doi: 10.1038/nature12297. Epub 2013 Jun 30. Nature. 2013. PMID: 23812589 Free PMC article.

6

Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells.

Shi LZ, Kalupahana NS, Turnis ME, Neale G, Hock H, Vignali DA, Chi H. Shi LZ, et al. Among authors: neale g. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3198-205. doi: 10.1073/pnas.1300950110. Epub 2013 Aug 5. Proc Natl Acad Sci U S A. 2013. PMID: 23918371 Free PMC article.

7

T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.

Yang K, Shrestha S, Zeng H, Karmaus PW, Neale G, Vogel P, Guertin DA, Lamb RF, Chi H. Yang K, et al. Among authors: neale g. Immunity. 2013 Dec 12;39(6):1043-56. doi: 10.1016/j.immuni.2013.09.015. Epub 2013 Dec 5. Immunity. 2013. PMID: 24315998 Free PMC article.

8

Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs.

Shrestha S, Yang K, Wei J, Karmaus PW, Neale G, Chi H. Shrestha S, et al. Among authors: neale g. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14858-63. doi: 10.1073/pnas.1404264111. Epub 2014 Sep 30. Proc Natl Acad Sci U S A. 2014. PMID: 25271321 Free PMC article.

9

Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways.

Haverkamp JM, Smith AM, Weinlich R, Dillon CP, Qualls JE, Neale G, Koss B, Kim Y, Bronte V, Herold MJ, Green DR, Opferman JT, Murray PJ. Haverkamp JM, et al. Among authors: neale g. Immunity. 2014 Dec 18;41(6):947-59. doi: 10.1016/j.immuni.2014.10.020. Epub 2014 Dec 11. Immunity. 2014. PMID: 25500368 Free PMC article.

10

Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.

Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Shrestha S, et al. Among authors: neale g. Nat Immunol. 2015 Feb;16(2):178-87. doi: 10.1038/ni.3076. Epub 2015 Jan 5. Nat Immunol. 2015. PMID: 25559258 Free PMC article.

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