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RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy.
Spang N, Feldmann A, Huesmann H, Bekbulat F, Schmitt V, Hiebel C, Koziollek-Drechsler I, Clement AM, Moosmann B, Jung J, Behrends C, Dikic I, Kern A, Behl C. Spang N, et al. Among authors: clement am. Autophagy. 2014;10(12):2297-309. doi: 10.4161/15548627.2014.994359. Autophagy. 2014. PMID: 25495476 Free PMC article.
Expression of the ALS-causing variant hSOD1(G93A) leads to an impaired integrity and altered regulation of claudin-5 expression in an in vitro blood-spinal cord barrier model.
Meister S, Storck SE, Hameister E, Behl C, Weggen S, Clement AM, Pietrzik CU. Meister S, et al. Among authors: clement am. J Cereb Blood Flow Metab. 2015 Jul;35(7):1112-21. doi: 10.1038/jcbfm.2015.57. Epub 2015 Apr 8. J Cereb Blood Flow Metab. 2015. PMID: 25853911 Free PMC article.
Receptor-mediated endocytosis 8 (RME-8)/DNAJC13 is a novel positive modulator of autophagy and stabilizes cellular protein homeostasis.
Besemer AS, Maus J, Ax MDA, Stein A, Vo S, Freese C, Nalbach K, von Hilchen C, Pfalzgraf IF, Koziollek-Drechsler I, Silva B, Huesmann H, Boukhallouk F, Florin L, Kern A, Behl C, Clement AM. Besemer AS, et al. Among authors: clement am. Cell Mol Life Sci. 2021 Jan;78(2):645-660. doi: 10.1007/s00018-020-03521-y. Epub 2020 Apr 22. Cell Mol Life Sci. 2021. PMID: 32322926 Free PMC article.
The K63 deubiquitinase CYLD modulates autism-like behaviors and hippocampal plasticity by regulating autophagy and mTOR signaling.
Colombo E, Horta G, Roesler MK, Ihbe N, Chhabra S, Radyushkin K, Di Liberto G, Kreutzfeldt M, Schumann S, von Engelhardt J, Merkler D, Behl C, Mittmann T, Clement AM, Waisman A, Schmeisser MJ. Colombo E, et al. Among authors: clement am. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2110755118. doi: 10.1073/pnas.2110755118. Proc Natl Acad Sci U S A. 2021. PMID: 34782467 Free PMC article.
62 results