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DNA damage, homology-directed repair, and DNA methylation.
Cuozzo C, Porcellini A, Angrisano T, Morano A, Lee B, Di Pardo A, Messina S, Iuliano R, Fusco A, Santillo MR, Muller MT, Chiariotti L, Gottesman ME, Avvedimento EV. Cuozzo C, et al. Among authors: avvedimento ev. PLoS Genet. 2007 Jul;3(7):e110. doi: 10.1371/journal.pgen.0030110. PLoS Genet. 2007. PMID: 17616978 Free PMC article.
Targeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene.
Morano A, Angrisano T, Russo G, Landi R, Pezone A, Bartollino S, Zuchegna C, Babbio F, Bonapace IM, Allen B, Muller MT, Chiariotti L, Gottesman ME, Porcellini A, Avvedimento EV. Morano A, et al. Among authors: avvedimento ev. Nucleic Acids Res. 2014 Jan;42(2):804-21. doi: 10.1093/nar/gkt920. Epub 2013 Oct 16. Nucleic Acids Res. 2014. PMID: 24137009 Free PMC article.
Targeted DNA oxidation by LSD1-SMAD2/3 primes TGF-β1/ EMT genes for activation or repression.
Pezone A, Taddei ML, Tramontano A, Dolcini J, Boffo FL, De Rosa M, Parri M, Stinziani S, Comito G, Porcellini A, Raugei G, Gackowski D, Zarakowska E, Olinski R, Gabrielli A, Chiarugi P, Avvedimento EV. Pezone A, et al. Among authors: avvedimento ev. Nucleic Acids Res. 2020 Sep 18;48(16):8943-8958. doi: 10.1093/nar/gkaa599. Nucleic Acids Res. 2020. PMID: 32697292 Free PMC article.
Tracing and tracking epiallele families in complex DNA populations.
Pezone A, Tramontano A, Scala G, Cuomo M, Riccio P, De Nicola S, Porcellini A, Chiariotti L, Avvedimento EV. Pezone A, et al. Among authors: avvedimento ev. NAR Genom Bioinform. 2020 Nov 16;2(4):lqaa096. doi: 10.1093/nargab/lqaa096. eCollection 2020 Dec. NAR Genom Bioinform. 2020. PMID: 33575640 Free PMC article.
DNA damage signatures in peripheral blood cells as biomarkers in prodromal huntington disease.
Castaldo I, De Rosa M, Romano A, Zuchegna C, Squitieri F, Mechelli R, Peluso S, Borrelli C, Del Mondo A, Salvatore E, Vescovi LA, Migliore S, De Michele G, Ristori G, Romano S, Avvedimento EV, Porcellini A. Castaldo I, et al. Among authors: avvedimento ev. Ann Neurol. 2019 Feb;85(2):296-301. doi: 10.1002/ana.25393. Epub 2019 Jan 13. Ann Neurol. 2019. PMID: 30549309
111 results