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Crystal structure of thrombin in complex with S-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors.
Koh CY, Kumar S, Kazimirova M, Nuttall PA, Radhakrishnan UP, Kim S, Jagadeeswaran P, Imamura T, Mizuguchi J, Iwanaga S, Swaminathan K, Kini RM. Koh CY, et al. Among authors: swaminathan k. PLoS One. 2011;6(10):e26367. doi: 10.1371/journal.pone.0026367. Epub 2011 Oct 28. PLoS One. 2011. PMID: 22053189 Free PMC article.
Avathrin: a novel thrombin inhibitor derived from a multicopy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum.
Iyer JK, Koh CY, Kazimirova M, Roller L, Jobichen C, Swaminathan K, Mizuguchi J, Iwanaga S, Nuttall PA, Chan MY, Kini RM. Iyer JK, et al. Among authors: swaminathan k. FASEB J. 2017 Jul;31(7):2981-2995. doi: 10.1096/fj.201601216R. Epub 2017 Mar 31. FASEB J. 2017. PMID: 28363953
Such precursor proteins that could be processed into multiple thrombin inhibiting peptides appear to be widespread among Amblyomminae, providing an enormous library of molecules for development as potent antithrombotics.-Iyer, J. K., Koh, C. Y., Kazimirova, M., Roller, L., …
Such precursor proteins that could be processed into multiple thrombin inhibiting peptides appear to be widespread among Amblyomminae, provi …
Crystallization and preliminary X-ray diffraction analysis of Salmonella typhi PilS.
Balakrishna AM, Tan YY, Mok HY, Saxena AM, Swaminathan K. Balakrishna AM, et al. Among authors: swaminathan k. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Oct 1;62(Pt 10):1024-6. doi: 10.1107/S174430910603661X. Epub 2006 Sep 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17012803 Free PMC article.
292 results