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Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-β-d-allofuranosyl)-2-nitroimidazole (β-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.
Wanek T, Kreis K, Križková P, Schweifer A, Denk C, Stanek J, Mairinger S, Filip T, Sauberer M, Edelhofer P, Traxl A, Muchitsch VE, Mereiter K, Hammerschmidt F, Cass CE, Damaraju VL, Langer O, Kuntner C. Wanek T, et al. Among authors: langer o. Bioorg Med Chem. 2016 Nov 1;24(21):5326-5339. doi: 10.1016/j.bmc.2016.08.053. Epub 2016 Aug 29. Bioorg Med Chem. 2016. PMID: 27614920
[18F]Ciprofloxacin, a new positron emission tomography tracer for noninvasive assessment of the tissue distribution and pharmacokinetics of ciprofloxacin in humans.
Brunner M, Langer O, Dobrozemsky G, Müller U, Zeitlinger M, Mitterhauser M, Wadsak W, Dudczak R, Kletter K, Müller M. Brunner M, et al. Among authors: langer o. Antimicrob Agents Chemother. 2004 Oct;48(10):3850-7. doi: 10.1128/AAC.48.10.3850-3857.2004. Antimicrob Agents Chemother. 2004. PMID: 15388445 Free PMC article. Clinical Trial.
A positron emission tomography microdosing study with a potential antiamyloid drug in healthy volunteers and patients with Alzheimer's disease.
Bauer M, Langer O, Dal-Bianco P, Karch R, Brunner M, Abrahim A, Lanzenberger R, Hofmann A, Joukhadar C, Carminati P, Ghirardi O, Piovesan P, Forloni G, Corrado ME, Lods N, Dudczak R, Auff E, Kletter K, Müller M. Bauer M, et al. Among authors: langer o. Clin Pharmacol Ther. 2006 Sep;80(3):216-27. doi: 10.1016/j.clpt.2006.05.007. Clin Pharmacol Ther. 2006. PMID: 16952488 Clinical Trial.
Synthesis and small-animal positron emission tomography evaluation of [11C]-elacridar as a radiotracer to assess the distribution of P-glycoprotein at the blood-brain barrier.
Dörner B, Kuntner C, Bankstahl JP, Bankstahl M, Stanek J, Wanek T, Stundner G, Mairinger S, Löscher W, Müller M, Langer O, Erker T. Dörner B, et al. Among authors: langer o. J Med Chem. 2009 Oct 8;52(19):6073-82. doi: 10.1021/jm900940f. J Med Chem. 2009. PMID: 19711894 Free PMC article.
Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[(11)C]verapamil PET.
Kuntner C, Bankstahl JP, Bankstahl M, Stanek J, Wanek T, Stundner G, Karch R, Brauner R, Meier M, Ding X, Müller M, Löscher W, Langer O. Kuntner C, et al. Among authors: langer o. Eur J Nucl Med Mol Imaging. 2010 May;37(5):942-53. doi: 10.1007/s00259-009-1332-5. Epub 2009 Dec 17. Eur J Nucl Med Mol Imaging. 2010. PMID: 20016890 Free PMC article.
393 results