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Synthetic 2-aryl-3-((piperidin-1-yl)ethyl)thiazolidin-4-ones exhibit selective in vitro antitumoral activity and inhibit cancer cell growth in a preclinical model of glioblastoma multiforme.
da Silveira EF, Azambuja JH, de Carvalho TR, Kunzler A, da Silva DS, Teixeira FC, Rodrigues R, Beira FT, de Cássia Sant Anna Alves R, Spanevello RM, Cunico W, Stefanello FM, Horn AP, Braganhol E. da Silveira EF, et al. Among authors: cunico w. Chem Biol Interact. 2017 Mar 25;266:1-9. doi: 10.1016/j.cbi.2017.02.001. Epub 2017 Feb 4. Chem Biol Interact. 2017. PMID: 28174097 Free article.
2-(2-Methoxyphenyl)-3-((Piperidin-1-yl)ethyl)thiazolidin-4-One-Loaded Polymeric Nanocapsules: In Vitro Antiglioma Activity and In Vivo Toxicity Evaluation.
da Silveira EF, Ferreira LM, Gehrcke M, Cruz L, Pedra NS, Ramos PT, Bona NP, Soares MSP, Rodrigues R, Spanevello RM, Cunico W, Stefanello FM, Azambuja JH, Horn AP, Braganhol E. da Silveira EF, et al. Among authors: cunico w. Cell Mol Neurobiol. 2019 Aug;39(6):783-797. doi: 10.1007/s10571-019-00678-4. Epub 2019 May 21. Cell Mol Neurobiol. 2019. PMID: 31115733
In Vitro Effects of 2-{4-[Methylthio(methylsulfonyl)]phenyl}-3-substitutedthiazolidin-4-ones on the Acetylcholinesterase Activity in Rat Brain and Lymphocytes: Isoform Selectivity, Kinetic Analysis, and Molecular Docking.
da Silva DS, Soares MSP, Martini F, Pesarico AP, de Mattos BDS, de Souza AA, da Silva CEH, Scaini JLR, Machado KDS, Wayne Nogueira C, Spanevello RM, Cunico W. da Silva DS, et al. Among authors: cunico w. Neurochem Res. 2020 Feb;45(2):241-253. doi: 10.1007/s11064-019-02929-8. Epub 2019 Dec 13. Neurochem Res. 2020. PMID: 31845170
Endophytic Fungus Isolated From Achyrocline satureioides Exhibits Selective Antiglioma Activity-The Role of Sch-642305.
Pedra NS, Galdino KCA, da Silva DS, Ramos PT, Bona NP, Soares MSP, Azambuja JH, Canuto KM, de Brito ES, Ribeiro PRV, Souza ASQ, Cunico W, Stefanello FM, Spanevello RM, Braganhol E. Pedra NS, et al. Among authors: cunico w. Front Oncol. 2018 Oct 29;8:476. doi: 10.3389/fonc.2018.00476. eCollection 2018. Front Oncol. 2018. PMID: 30420941 Free PMC article.
Synthesis of thiazolidin-4-ones and thiazinan-4-ones from 1-(2-aminoethyl)pyrrolidine as acetylcholinesterase inhibitors.
das Neves AM, Berwaldt GA, Avila CT, Goulart TB, Moreira BC, Ferreira TP, Soares MSP, Pedra NS, Spohr L, dE Souza AAA, Spanevello RM, Cunico W. das Neves AM, et al. Among authors: cunico w. J Enzyme Inhib Med Chem. 2020 Dec;35(1):31-41. doi: 10.1080/14756366.2019.1680659. J Enzyme Inhib Med Chem. 2020. PMID: 31645149 Free PMC article.
Effect of Thiazolidin-4-one Against Lipopolysaccharide-Induced Oxidative Damage, and Alterations in Adenine Nucleotide Hydrolysis and Acetylcholinesterase Activity in Cultured Astrocytes.
Alvez FL, Bona NP, Pedra NS, da Silva DS, Cunico WJ, Stefanello FM, de Andrade CM, Soares MSP, Spanevello RM. Alvez FL, et al. Among authors: cunico wj. Cell Mol Neurobiol. 2023 Jan;43(1):283-297. doi: 10.1007/s10571-021-01177-1. Epub 2022 Jan 15. Cell Mol Neurobiol. 2023. PMID: 35031909
47 results