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PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer's disease model.
Katsouri L, Lim YM, Blondrath K, Eleftheriadou I, Lombardero L, Birch AM, Mirzaei N, Irvine EE, Mazarakis ND, Sastre M. Katsouri L, et al. Among authors: blondrath k. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12292-12297. doi: 10.1073/pnas.1606171113. Epub 2016 Oct 10. Proc Natl Acad Sci U S A. 2016. PMID: 27791018 Free PMC article.