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Do More With Less: Tips and Techniques for Maximizing Small Biopsy and Cytology Specimens for Molecular and Ancillary Testing: The University of Colorado Experience.
Aisner DL, Rumery MD, Merrick DT, Kondo KL, Nijmeh H, Linderman DJ, Doebele RC, Thomas N, Chesnut PC, Varella-Garcia M, Franklin WA, Camidge DR. Aisner DL, et al. Among authors: doebele rc. Arch Pathol Lab Med. 2016 Nov;140(11):1206-1220. doi: 10.5858/arpa.2016-0156-RA. Epub 2016 Sep 9. Arch Pathol Lab Med. 2016. PMID: 27610643 Free PMC article.
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression.
Chuang TP, Lai WY, Gabre JL, Lind DE, Umapathy G, Bokhari AA, Bergman B, Kristenson L, Thorén FB, Le A, Doebele RC, Van den Eynden J, Palmer RH, Hallberg B. Chuang TP, et al. Among authors: doebele rc. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2216479120. doi: 10.1073/pnas.2216479120. Epub 2023 Feb 15. Proc Natl Acad Sci U S A. 2023. PMID: 36791109 Free PMC article.
Biomarkers are here to stay for clinical research and standard care.
Bunn PA Jr, Hirsch FR, Doebele RC, Camidge DR, Varella-Garcia M, Franklin W. Bunn PA Jr, et al. Among authors: doebele rc. J Thorac Oncol. 2010 Aug;5(8):1113-5. doi: 10.1097/JTO.0b013e3181e7616e. J Thorac Oncol. 2010. PMID: 20661083 Free article. No abstract available.
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment.
Camidge DR, Kono SA, Flacco A, Tan AC, Doebele RC, Zhou Q, Crino L, Franklin WA, Varella-Garcia M. Camidge DR, et al. Among authors: doebele rc. Clin Cancer Res. 2010 Nov 15;16(22):5581-90. doi: 10.1158/1078-0432.CCR-10-0851. Epub 2010 Nov 9. Clin Cancer Res. 2010. PMID: 21062932 Free PMC article.
A phase I/II study of erlotinib in combination with the anti-insulin-like growth factor-1 receptor monoclonal antibody IMC-A12 (cixutumumab) in patients with advanced non-small cell lung cancer.
Weickhardt A, Doebele R, Oton A, Lettieri J, Maxson D, Reynolds M, Brown A, Jackson MK, Dy G, Adjei A, Fetterly G, Lu X, Franklin W, Varella-Garcia M, Hirsch FR, Wynes MW, Youssoufian H, Adjei A, Camidge DR. Weickhardt A, et al. J Thorac Oncol. 2012 Feb;7(2):419-26. doi: 10.1097/JTO.0b013e31823c5b11. J Thorac Oncol. 2012. PMID: 22237261 Free PMC article. Clinical Trial.
Correlations between the percentage of tumor cells showing an anaplastic lymphoma kinase (ALK) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization-positive nonsmall cell lung cancer.
Camidge DR, Theodoro M, Maxson DA, Skokan M, O'Brien T, Lu X, Doebele RC, Barón AE, Varella-Garcia M. Camidge DR, et al. Among authors: doebele rc. Cancer. 2012 Sep 15;118(18):4486-94. doi: 10.1002/cncr.27411. Epub 2012 Jan 26. Cancer. 2012. PMID: 22282074 Free PMC article.
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