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Page 1
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Mayers JR, Torrence ME, Danai LV, Papagiannakopoulos T, Davidson SM, Bauer MR, Lau AN, Ji BW, Dixit PD, Hosios AM, Muir A, Chin CR, Freinkman E, Jacks T, Wolpin BM, Vitkup D, Vander Heiden MG. Mayers JR, et al. Among authors: jacks t. Science. 2016 Sep 9;353(6304):1161-5. doi: 10.1126/science.aaf5171. Science. 2016. PMID: 27609895 Free PMC article.
p53 status and the efficacy of cancer therapy in vivo.
Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, Housman DE, Jacks T. Lowe SW, et al. Among authors: jacks t. Science. 1994 Nov 4;266(5186):807-10. doi: 10.1126/science.7973635. Science. 1994. PMID: 7973635
Mouse models of tumor development in neurofibromatosis type 1.
Cichowski K, Shih TS, Schmitt E, Santiago S, Reilly K, McLaughlin ME, Bronson RT, Jacks T. Cichowski K, et al. Among authors: jacks t. Science. 1999 Dec 10;286(5447):2172-6. doi: 10.1126/science.286.5447.2172. Science. 1999. PMID: 10591652
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC. Barbie DA, et al. Among authors: jacks t. Nature. 2009 Nov 5;462(7269):108-12. doi: 10.1038/nature08460. Epub 2009 Oct 21. Nature. 2009. PMID: 19847166 Free PMC article.
Context-dependent transformation of adult pancreatic cells by oncogenic K-Ras.
Gidekel Friedlander SY, Chu GC, Snyder EL, Girnius N, Dibelius G, Crowley D, Vasile E, DePinho RA, Jacks T. Gidekel Friedlander SY, et al. Among authors: jacks t. Cancer Cell. 2009 Nov 6;16(5):379-89. doi: 10.1016/j.ccr.2009.09.027. Cancer Cell. 2009. PMID: 19878870 Free PMC article.
p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis.
Kirsch DG, Santiago PM, di Tomaso E, Sullivan JM, Hou WS, Dayton T, Jeffords LB, Sodha P, Mercer KL, Cohen R, Takeuchi O, Korsmeyer SJ, Bronson RT, Kim CF, Haigis KM, Jain RK, Jacks T. Kirsch DG, et al. Among authors: jacks t. Science. 2010 Jan 29;327(5965):593-6. doi: 10.1126/science.1166202. Epub 2009 Dec 17. Science. 2010. PMID: 20019247 Free PMC article.
Immunology. Guilty by association.
Joshi NS, Jacks T. Joshi NS, et al. Among authors: jacks t. Science. 2013 Mar 8;339(6124):1160-1. doi: 10.1126/science.1235528. Science. 2013. PMID: 23471395 No abstract available.
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.
Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, Burga LN, Xie J, Jurczak MJ, DePinho RA, Clish CB, Jacks T, Kibbey RG, Wulf GM, Di Vizio D, Mills GB, Cantley LC, Vander Heiden MG. Israelsen WJ, et al. Among authors: jacks t. Cell. 2013 Oct 10;155(2):397-409. doi: 10.1016/j.cell.2013.09.025. Cell. 2013. PMID: 24120138 Free PMC article.
Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing.
McFadden DG, Papagiannakopoulos T, Taylor-Weiner A, Stewart C, Carter SL, Cibulskis K, Bhutkar A, McKenna A, Dooley A, Vernon A, Sougnez C, Malstrom S, Heimann M, Park J, Chen F, Farago AF, Dayton T, Shefler E, Gabriel S, Getz G, Jacks T. McFadden DG, et al. Among authors: jacks t. Cell. 2014 Mar 13;156(6):1298-1311. doi: 10.1016/j.cell.2014.02.031. Cell. 2014. PMID: 24630729 Free PMC article.
438 results