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Page 1
Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients.
Zaharenko L, Kalnina I, Geldnere K, Konrade I, Grinberga S, Židzik J, Javorský M, Lejnieks A, Nikitina-Zake L, Fridmanis D, Peculis R, Radovica-Spalvina I, Hartmane D, Pugovics O, Tkáč I, Klimčáková L, Pīrāgs V, Klovins J. Zaharenko L, et al. Eur J Endocrinol. 2016 Dec;175(6):531-540. doi: 10.1530/EJE-16-0347. Epub 2016 Sep 8. Eur J Endocrinol. 2016. PMID: 27609360
Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals.
Elbere I, Silamikelis I, Ustinova M, Kalnina I, Zaharenko L, Peculis R, Konrade I, Ciuculete DM, Zhukovsky C, Gudra D, Radovica-Spalvina I, Fridmanis D, Pirags V, Schiöth HB, Klovins J. Elbere I, et al. Clin Epigenetics. 2018 Dec 13;10(1):156. doi: 10.1186/s13148-018-0593-x. Clin Epigenetics. 2018. PMID: 30545422 Free PMC article. Clinical Trial.
Control of Acinetobacter baumannii outbreak in the neonatal intensive care unit in Latvia: whole-genome sequencing powered investigation and closure of the ward.
Gramatniece A, Silamikelis I, Zahare I, Urtans V, Zahare I, Dimina E, Saule M, Balode A, Radovica-Spalvina I, Klovins J, Fridmanis D, Dumpis U. Gramatniece A, et al. Among authors: radovica spalvina i. Antimicrob Resist Infect Control. 2019 May 22;8:84. doi: 10.1186/s13756-019-0537-z. eCollection 2019. Antimicrob Resist Infect Control. 2019. PMID: 31143444 Free PMC article.
Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals.
Ustinova M, Silamikelis I, Kalnina I, Ansone L, Rovite V, Elbere I, Radovica-Spalvina I, Fridmanis D, Aladyeva J, Konrade I, Pirags V, Klovins J. Ustinova M, et al. Among authors: radovica spalvina i. PLoS One. 2019 Nov 8;14(11):e0224835. doi: 10.1371/journal.pone.0224835. eCollection 2019. PLoS One. 2019. PMID: 31703101 Free PMC article.
Case report: recurrent pituitary adenoma has increased load of somatic variants.
Peculis R, Balcere I, Radovica-Spalvina I, Konrade I, Caune O, Megnis K, Rovite V, Stukens J, Nazarovs J, Breiksa A, Kiecis A, Silamikelis I, Pirags V, Klovins J. Peculis R, et al. Among authors: radovica spalvina i. BMC Endocr Disord. 2020 Jan 29;20(1):17. doi: 10.1186/s12902-020-0493-x. BMC Endocr Disord. 2020. PMID: 31996211 Free PMC article.
17 results