Begley D - Search Results

1

Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses.

Kirkegaard T, Gray J, Priestman DA, Wallom KL, Atkins J, Olsen OD, Klein A, Drndarski S, Petersen NH, Ingemann L, Smith DA, Morris L, Bornæs C, Jørgensen SH, Williams I, Hinsby A, Arenz C, Begley D, Jäättelä M, Platt FM. Kirkegaard T, et al. Among authors: begley d. Sci Transl Med. 2016 Sep 7;8(355):355ra118. doi: 10.1126/scitranslmed.aad9823. Sci Transl Med. 2016. PMID: 27605553 Free PMC article.

2

Cyclodextrin alleviates neuronal storage of cholesterol in Niemann-Pick C disease without evidence of detectable blood-brain barrier permeability.

Pontikis CC, Davidson CD, Walkley SU, Platt FM, Begley DJ. Pontikis CC, et al. Among authors: begley dj. J Inherit Metab Dis. 2013 May;36(3):491-8. doi: 10.1007/s10545-012-9583-x. Epub 2013 Feb 15. J Inherit Metab Dis. 2013. PMID: 23412751 Free PMC article.

3

Stroke Recovery in Rats after 24-Hour-Delayed Intramuscular Neurotrophin-3 Infusion.

Duricki DA, Drndarski S, Bernanos M, Wood T, Bosch K, Chen Q, Shine HD, Simmons C, Williams SCR, McMahon SB, Begley DJ, Cash D, Moon LDF. Duricki DA, et al. Among authors: begley dj. Ann Neurol. 2019 Jan;85(1):32-46. doi: 10.1002/ana.25386. Epub 2018 Dec 28. Ann Neurol. 2019. PMID: 30525223 Free PMC article.

4

The blood-brain barrier: principles for targeting peptides and drugs to the central nervous system.

Begley DJ. Begley DJ. J Pharm Pharmacol. 1996 Feb;48(2):136-46. doi: 10.1111/j.2042-7158.1996.tb07112.x. J Pharm Pharmacol. 1996. PMID: 8935161 Review.

5

The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein.

Watson CP, Dogruel M, Mihoreanu L, Begley DJ, Weksler BB, Couraud PO, Romero IA, Thomas SA. Watson CP, et al. Brain Res. 2012 Feb 3;1436:111-21. doi: 10.1016/j.brainres.2011.11.053. Epub 2011 Dec 4. Brain Res. 2012. PMID: 22200378 Free PMC article.

6

Intrathecal delivery of protein therapeutics to the brain: a critical reassessment.

Calias P, Banks WA, Begley D, Scarpa M, Dickson P. Calias P, et al. Among authors: begley d. Pharmacol Ther. 2014 Nov;144(2):114-22. doi: 10.1016/j.pharmthera.2014.05.009. Epub 2014 May 20. Pharmacol Ther. 2014. PMID: 24854599 Free article. Review.

7

Lysosomal storage diseases and the blood-brain barrier.

Begley DJ, Pontikis CC, Scarpa M. Begley DJ, et al. Curr Pharm Des. 2008;14(16):1566-80. doi: 10.2174/138161208784705504. Curr Pharm Des. 2008. PMID: 18673198 Review.

8

Human serum albumin nanoparticles modified with apolipoprotein A-I cross the blood-brain barrier and enter the rodent brain.

Zensi A, Begley D, Pontikis C, Legros C, Mihoreanu L, Büchel C, Kreuter J. Zensi A, et al. Among authors: begley d. J Drug Target. 2010 Dec;18(10):842-8. doi: 10.3109/1061186X.2010.513712. Epub 2010 Sep 20. J Drug Target. 2010. PMID: 20849354

9

Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones.

Zensi A, Begley D, Pontikis C, Legros C, Mihoreanu L, Wagner S, Büchel C, von Briesen H, Kreuter J. Zensi A, et al. Among authors: begley d. J Control Release. 2009 Jul 1;137(1):78-86. doi: 10.1016/j.jconrel.2009.03.002. Epub 2009 Mar 11. J Control Release. 2009. PMID: 19285109

10

Structure and function of the blood-brain barrier.

Abbott NJ, Patabendige AA, Dolman DE, Yusof SR, Begley DJ. Abbott NJ, et al. Neurobiol Dis. 2010 Jan;37(1):13-25. doi: 10.1016/j.nbd.2009.07.030. Epub 2009 Aug 5. Neurobiol Dis. 2010. PMID: 19664713 Review.

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