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Molecular signatures associated with ZIKV exposure in human cortical neural progenitors.
Zhang F, Hammack C, Ogden SC, Cheng Y, Lee EM, Wen Z, Qian X, Nguyen HN, Li Y, Yao B, Xu M, Xu T, Chen L, Wang Z, Feng H, Huang WK, Yoon KJ, Shan C, Huang L, Qin Z, Christian KM, Shi PY, Xu M, Xia M, Zheng W, Wu H, Song H, Tang H, Ming GL, Jin P. Zhang F, et al. Among authors: xia m. Nucleic Acids Res. 2016 Oct 14;44(18):8610-8620. doi: 10.1093/nar/gkw765. Epub 2016 Aug 31. Nucleic Acids Res. 2016. PMID: 27580721 Free PMC article.
Identification of HDAC Inhibitors Using a Cell-Based HDAC I/II Assay.
Hsu CW, Shou D, Huang R, Khuc T, Dai S, Zheng W, Klumpp-Thomas C, Xia M. Hsu CW, et al. Among authors: xia m. J Biomol Screen. 2016 Jul;21(6):643-52. doi: 10.1177/1087057116629381. Epub 2016 Feb 8. J Biomol Screen. 2016. PMID: 26858181 Free PMC article.
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.
Xu M, Lee EM, Wen Z, Cheng Y, Huang WK, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael SG, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H. Xu M, et al. Among authors: xia m. Nat Med. 2016 Oct;22(10):1101-1107. doi: 10.1038/nm.4184. Epub 2016 Aug 29. Nat Med. 2016. PMID: 27571349 Free PMC article.
Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction.
Li Z, Brecher M, Deng YQ, Zhang J, Sakamuru S, Liu B, Huang R, Koetzner CA, Allen CA, Jones SA, Chen H, Zhang NN, Tian M, Gao F, Lin Q, Banavali N, Zhou J, Boles N, Xia M, Kramer LD, Qin CF, Li H. Li Z, et al. Among authors: xia m. Cell Res. 2017 Aug;27(8):1046-1064. doi: 10.1038/cr.2017.88. Epub 2017 Jul 7. Cell Res. 2017. PMID: 28685770 Free PMC article.
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.
Yang S, Xu M, Lee EM, Gorshkov K, Shiryaev SA, He S, Sun W, Cheng YS, Hu X, Tharappel AM, Lu B, Pinto A, Farhy C, Huang CT, Zhang Z, Zhu W, Wu Y, Zhou Y, Song G, Zhu H, Shamim K, Martínez-Romero C, García-Sastre A, Preston RA, Jayaweera DT, Huang R, Huang W, Xia M, Simeonov A, Ming G, Qiu X, Terskikh AV, Tang H, Song H, Zheng W. Yang S, et al. Among authors: xia m. Cell Discov. 2018 Jun 5;4:31. doi: 10.1038/s41421-018-0034-1. eCollection 2018. Cell Discov. 2018. PMID: 29872540 Free PMC article.
An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication.
Song G, Lee EM, Pan J, Xu M, Rho HS, Cheng Y, Whitt N, Yang S, Kouznetsova J, Klumpp-Thomas C, Michael SG, Moore C, Yoon KJ, Christian KM, Simeonov A, Huang W, Xia M, Huang R, Lal-Nag M, Tang H, Zheng W, Qian J, Song H, Ming GL, Zhu H. Song G, et al. Among authors: xia m. Genomics Proteomics Bioinformatics. 2021 Feb;19(1):108-122. doi: 10.1016/j.gpb.2020.06.016. Epub 2021 Feb 19. Genomics Proteomics Bioinformatics. 2021. PMID: 33610792 Free PMC article.
Biological activity-based modeling identifies antiviral leads against SARS-CoV-2.
Huang R, Xu M, Zhu H, Chen CZ, Zhu W, Lee EM, He S, Zhang L, Zhao J, Shamim K, Bougie D, Huang W, Xia M, Hall MD, Lo D, Simeonov A, Austin CP, Qiu X, Tang H, Zheng W. Huang R, et al. Among authors: xia m. Nat Biotechnol. 2021 Jun;39(6):747-753. doi: 10.1038/s41587-021-00839-1. Epub 2021 Feb 23. Nat Biotechnol. 2021. PMID: 33623157 Free PMC article.
3,640 results