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Phase I/II study of intrapleural administration of a serotype rh.10 replication-deficient adeno-associated virus gene transfer vector expressing the human α1-antitrypsin cDNA to individuals with α1-antitrypsin deficiency.
Chiuchiolo MJ, Kaminsky SM, Sondhi D, Mancenido D, Hollmann C, Crystal RG. Chiuchiolo MJ, et al. Hum Gene Ther Clin Dev. 2014 Sep;25(3):112-33. doi: 10.1089/humc.2014.2513. Hum Gene Ther Clin Dev. 2014. PMID: 25238276 Clinical Trial. No abstract available.
Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors.
Kothari P, De BP, He B, Chen A, Chiuchiolo MJ, Kim D, Nikolopoulou A, Amor-Coarasa A, Dyke JP, Voss HU, Kaminsky SM, Foley CP, Vallabhajosula S, Hu B, DiMagno SG, Sondhi D, Crystal RG, Babich JW, Ballon D. Kothari P, et al. Among authors: chiuchiolo mj. Sci Rep. 2017 Jan 6;7:39594. doi: 10.1038/srep39594. Sci Rep. 2017. PMID: 28059103 Free PMC article.
"Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors.
Mathison M, Singh VP, Gersch RP, Ramirez MO, Cooney A, Kaminsky SM, Chiuchiolo MJ, Nasser A, Yang J, Crystal RG, Rosengart TK. Mathison M, et al. Among authors: chiuchiolo mj. J Thorac Cardiovasc Surg. 2014 Oct;148(4):1656-1664.e2. doi: 10.1016/j.jtcvs.2014.03.033. Epub 2014 Mar 27. J Thorac Cardiovasc Surg. 2014. PMID: 24755332 Free article.
Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma.
Hicks MJ, Funato K, Wang L, Aronowitz E, Dyke JP, Ballon DJ, Havlicek DF, Frenk EZ, De BP, Chiuchiolo MJ, Sondhi D, Hackett NR, Kaminsky SM, Tabar V, Crystal RG. Hicks MJ, et al. Among authors: chiuchiolo mj. Cancer Gene Ther. 2015 Jan;22(1):1-8. doi: 10.1038/cgt.2014.58. Epub 2014 Dec 12. Cancer Gene Ther. 2015. PMID: 25501993 Free PMC article.
30 results