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Regulation of Polycystin-1 Function by Calmodulin Binding.
Doerr N, Wang Y, Kipp KR, Liu G, Benza JJ, Pletnev V, Pavlov TS, Staruschenko A, Mohieldin AM, Takahashi M, Nauli SM, Weimbs T. Doerr N, et al. Among authors: weimbs t. PLoS One. 2016 Aug 25;11(8):e0161525. doi: 10.1371/journal.pone.0161525. eCollection 2016. PLoS One. 2016. PMID: 27560828 Free PMC article.
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.
Shillingford JM, Murcia NS, Larson CH, Low SH, Hedgepeth R, Brown N, Flask CA, Novick AC, Goldfarb DA, Kramer-Zucker A, Walz G, Piontek KB, Germino GG, Weimbs T. Shillingford JM, et al. Among authors: weimbs t. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5466-71. doi: 10.1073/pnas.0509694103. Epub 2006 Mar 27. Proc Natl Acad Sci U S A. 2006. PMID: 16567633 Free PMC article.
Polycystin-1 regulates STAT activity by a dual mechanism.
Talbot JJ, Shillingford JM, Vasanth S, Doerr N, Mukherjee S, Kinter MT, Watnick T, Weimbs T. Talbot JJ, et al. Among authors: weimbs t. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7985-90. doi: 10.1073/pnas.1103816108. Epub 2011 Apr 25. Proc Natl Acad Sci U S A. 2011. PMID: 21518865 Free PMC article.
Bicc1 Polymerization Regulates the Localization and Silencing of Bound mRNA.
Rothé B, Leal-Esteban L, Bernet F, Urfer S, Doerr N, Weimbs T, Iwaszkiewicz J, Constam DB. Rothé B, et al. Among authors: weimbs t. Mol Cell Biol. 2015 Oct;35(19):3339-53. doi: 10.1128/MCB.00341-15. Epub 2015 Jul 27. Mol Cell Biol. 2015. PMID: 26217012 Free PMC article.
75 results