Jiang Q - Search Results

1

Discovery of novel xanthine compounds targeting DPP-IV and GPR119 as anti-diabetic agents.

Li G, Huan Y, Yuan B, Wang J, Jiang Q, Lin Z, Shen Z, Huang H. Li G, et al. Among authors: jiang q. Eur J Med Chem. 2016 Nov 29;124:103-116. doi: 10.1016/j.ejmech.2016.08.023. Epub 2016 Aug 13. Eur J Med Chem. 2016. PMID: 27560285

2

Effects and Potential Mechanisms of Pioglitazone on Lipid Metabolism in Obese Diabetic KKAy Mice.

Peng J, Huan Y, Jiang Q, Sun SJ, Jia CM, Shen ZF. Peng J, et al. Among authors: jiang q. PPAR Res. 2014;2014:538183. doi: 10.1155/2014/538183. Epub 2014 Mar 31. PPAR Res. 2014. PMID: 24799887 Free PMC article.

3

Establishment of a dipeptidyl peptidases (DPP) 8/9 expressing cell model for evaluating the selectivity of DPP4 inhibitors.

Huan Y, Jiang Q, Liu JL, Shen ZF. Huan Y, et al. Among authors: jiang q. J Pharmacol Toxicol Methods. 2015 Jan-Feb;71:8-12. doi: 10.1016/j.vascn.2014.11.002. Epub 2014 Nov 15. J Pharmacol Toxicol Methods. 2015. PMID: 25464020

4

Effect of Chronic Pioglitazone Treatment on Hepatic Gene Expression Profile in Obese C57BL/6J Mice.

Jia C, Huan Y, Liu S, Hou S, Sun S, Li C, Liu Q, Jiang Q, Wang Y, Shen Z. Jia C, et al. Among authors: jiang q. Int J Mol Sci. 2015 May 29;16(6):12213-29. doi: 10.3390/ijms160612213. Int J Mol Sci. 2015. PMID: 26035752 Free PMC article.

5

[Farnesoid X receptor regulates glucose and lipid metabolisms].

Jiang Q, Peng J, Liu SN, Shen ZF. Jiang Q, et al. Yao Xue Xue Bao. 2015 Mar;50(3):245-51. Yao Xue Xue Bao. 2015. PMID: 26118101 Chinese.

6

Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db Mice.

Hou S, Li C, Huan Y, Liu S, Liu Q, Sun S, Jiang Q, Jia C, Shen Z. Hou S, et al. Among authors: jiang q. J Diabetes Res. 2015;2015:817839. doi: 10.1155/2015/817839. Epub 2015 Aug 17. J Diabetes Res. 2015. PMID: 26351642 Free PMC article.

7

Synthesis and biological evaluations of chalcones, flavones and chromenes as farnesoid x receptor (FXR) antagonists.

Zhang G, Liu S, Tan W, Verma R, Chen Y, Sun D, Huan Y, Jiang Q, Wang X, Wang N, Xu Y, Wong C, Shen Z, Deng R, Liu J, Zhang Y, Fang W. Zhang G, et al. Among authors: jiang q. Eur J Med Chem. 2017 Mar 31;129:303-309. doi: 10.1016/j.ejmech.2017.02.037. Epub 2017 Feb 20. Eur J Med Chem. 2017. PMID: 28235703 Free PMC article.

8

The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo.

Huan Y, Jiang Q, Li G, Bai G, Zhou T, Liu S, Li C, Liu Q, Sun S, Yang M, Guo N, Wang X, Wang S, Liu Y, Wang G, Huang H, Shen Z. Huan Y, et al. Among authors: jiang q. Sci Rep. 2017 Jun 28;7(1):4351. doi: 10.1038/s41598-017-04633-5. Sci Rep. 2017. PMID: 28659588 Free PMC article.

9

The optimization of xanthine derivatives leading to HBK001 hydrochloride as a potent dual ligand targeting DPP-IV and GPR119.

Li G, Meng B, Yuan B, Huan Y, Zhou T, Jiang Q, Lei L, Sheng L, Wang W, Gong N, Lu Y, Ma C, Li Y, Shen Z, Huang H. Li G, et al. Among authors: jiang q. Eur J Med Chem. 2020 Feb 15;188:112017. doi: 10.1016/j.ejmech.2019.112017. Epub 2019 Dec 31. Eur J Med Chem. 2020. PMID: 31926470

10

Insulin induces insulin receptor degradation in the liver through EphB4.

Liu X, Wang K, Hou S, Jiang Q, Ma C, Zhao Q, Kong L, Chen J, Wang Z, Zhang H, Yuan T, Li Y, Huan Y, Shen Z, Hu Z, Huang Z, Cui B, Li P. Liu X, et al. Among authors: jiang q. Nat Metab. 2022 Sep;4(9):1202-1213. doi: 10.1038/s42255-022-00634-5. Epub 2022 Sep 21. Nat Metab. 2022. PMID: 36131205

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