Boschert V - Search Results

1

The sclerostin-neutralizing antibody AbD09097 recognizes an epitope adjacent to sclerostin's binding site for the Wnt co-receptor LRP6.

Boschert V, Frisch C, Back JW, van Pee K, Weidauer SE, Muth EM, Schmieder P, Beerbaum M, Knappik A, Timmerman P, Mueller TD. Boschert V, et al. Open Biol. 2016 Aug;6(8):160120. doi: 10.1098/rsob.160120. Open Biol. 2016. PMID: 27558933 Free PMC article.

2

Anti-Sclerostin antibody inhibits internalization of Sclerostin and Sclerostin-mediated antagonism of Wnt/LRP6 signaling.

van Dinther M, Zhang J, Weidauer SE, Boschert V, Muth EM, Knappik A, de Gorter DJ, van Kasteren PB, Frisch C, Mueller TD, ten Dijke P. van Dinther M, et al. Among authors: boschert v. PLoS One. 2013 Apr 29;8(4):e62295. doi: 10.1371/journal.pone.0062295. Print 2013. PLoS One. 2013. PMID: 23638027 Free PMC article.

3

Mutational analysis of sclerostin shows importance of the flexible loop and the cystine-knot for Wnt-signaling inhibition.

Boschert V, van Dinther M, Weidauer S, van Pee K, Muth EM, Ten Dijke P, Mueller TD. Boschert V, et al. PLoS One. 2013 Nov 29;8(11):e81710. doi: 10.1371/journal.pone.0081710. eCollection 2013. PLoS One. 2013. PMID: 24312339 Free PMC article.

4

Crystallization and preliminary X-ray crystallographic analysis of the sclerostin-neutralizing Fab AbD09097.

Boschert V, Muth EM, Knappik A, Frisch C, Mueller TD. Boschert V, et al. Acta Crystallogr F Struct Biol Commun. 2015 Apr;71(Pt 4):388-92. doi: 10.1107/S2053230X1500360X. Epub 2015 Mar 20. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25849496 Free PMC article.

5

Selecting highly structure-specific antibodies using structured synthetic mimics of the cystine knot protein sclerostin.

Back JW, Frisch C, Van Pee K, Boschert V, van Vught R, Puijk W, Mueller TD, Knappik A, Timmerman P. Back JW, et al. Among authors: boschert v. Protein Eng Des Sel. 2012 May;25(5):251-9. doi: 10.1093/protein/gzs012. Epub 2012 Mar 27. Protein Eng Des Sel. 2012. PMID: 22454505

6

Single chain TNF derivatives with individually mutated receptor binding sites reveal differential stoichiometry of ligand receptor complex formation for TNFR1 and TNFR2.

Boschert V, Krippner-Heidenreich A, Branschädel M, Tepperink J, Aird A, Scheurich P. Boschert V, et al. Cell Signal. 2010 Jul;22(7):1088-96. doi: 10.1016/j.cellsig.2010.02.011. Epub 2010 Mar 4. Cell Signal. 2010. PMID: 20206684

7

The tumor necrosis factor receptor stalk regions define responsiveness to soluble versus membrane-bound ligand.

Richter C, Messerschmidt S, Holeiter G, Tepperink J, Osswald S, Zappe A, Branschädel M, Boschert V, Mann DA, Scheurich P, Krippner-Heidenreich A. Richter C, et al. Among authors: boschert v. Mol Cell Biol. 2012 Jul;32(13):2515-29. doi: 10.1128/MCB.06458-11. Epub 2012 Apr 30. Mol Cell Biol. 2012. PMID: 22547679 Free PMC article.

8

The Influence of Met Receptor Level on HGF-Induced Glycolytic Reprogramming in Head and Neck Squamous Cell Carcinoma.

Boschert V, Klenk N, Abt A, Janaki Raman S, Fischer M, Brands RC, Seher A, Linz C, Müller-Richter UDA, Bischler T, Hartmann S. Boschert V, et al. Int J Mol Sci. 2020 Jan 11;21(2):471. doi: 10.3390/ijms21020471. Int J Mol Sci. 2020. PMID: 31940827 Free PMC article.

9

HGF-Induced PD-L1 Expression in Head and Neck Cancer: Preclinical and Clinical Findings.

Boschert V, Teusch J, Aljasem A, Schmucker P, Klenk N, Straub A, Bittrich M, Seher A, Linz C, Müller-Richter UDA, Hartmann S. Boschert V, et al. Int J Mol Sci. 2020 Nov 20;21(22):8770. doi: 10.3390/ijms21228770. Int J Mol Sci. 2020. PMID: 33233528 Free PMC article.

10

PKM2 Modulation in Head and Neck Squamous Cell Carcinoma.

Boschert V, Teusch J, Müller-Richter UDA, Brands RC, Hartmann S. Boschert V, et al. Int J Mol Sci. 2022 Jan 11;23(2):775. doi: 10.3390/ijms23020775. Int J Mol Sci. 2022. PMID: 35054968 Free PMC article.

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