Leanza L - Search Results

1

Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma.

Zaccagnino A, Managò A, Leanza L, Gontarewitz A, Linder B, Azzolini M, Biasutto L, Zoratti M, Peruzzo R, Legler K, Trauzold A, Kalthoff H, Szabo I. Zaccagnino A, et al. Among authors: leanza l. Oncotarget. 2017 Jun 13;8(24):38276-38293. doi: 10.18632/oncotarget.11299. Oncotarget. 2017. PMID: 27542263 Free PMC article.

2

Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax- and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis.

Szabò I, Soddemann M, Leanza L, Zoratti M, Gulbins E. Szabò I, et al. Among authors: leanza l. Cell Death Differ. 2011 Mar;18(3):427-38. doi: 10.1038/cdd.2010.112. Epub 2010 Oct 1. Cell Death Differ. 2011. PMID: 20885444 Free PMC article.

3

Physiology of potassium channels in the inner membrane of mitochondria.

Szabò I, Leanza L, Gulbins E, Zoratti M. Szabò I, et al. Among authors: leanza l. Pflugers Arch. 2012 Feb;463(2):231-46. doi: 10.1007/s00424-011-1058-7. Epub 2011 Nov 18. Pflugers Arch. 2012. PMID: 22089812 Review.

4

Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells.

Leanza L, Henry B, Sassi N, Zoratti M, Chandy KG, Gulbins E, Szabò I. Leanza L, et al. EMBO Mol Med. 2012 Jul;4(7):577-93. doi: 10.1002/emmm.201200235. Epub 2012 Apr 11. EMBO Mol Med. 2012. PMID: 22496117 Free PMC article.

5

Thylakoid potassium channel is required for efficient photosynthesis in cyanobacteria.

Checchetto V, Segalla A, Allorent G, La Rocca N, Leanza L, Giacometti GM, Uozumi N, Finazzi G, Bergantino E, Szabò I. Checchetto V, et al. Among authors: leanza l. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):11043-8. doi: 10.1073/pnas.1205960109. Epub 2012 Jun 18. Proc Natl Acad Sci U S A. 2012. PMID: 22711813 Free PMC article.

6

Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels.

Leanza L, Zoratti M, Gulbins E, Szabò I. Leanza L, et al. Curr Med Chem. 2012;19(31):5394-404. doi: 10.2174/092986712803833281. Curr Med Chem. 2012. PMID: 22856664

7

Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia.

Leanza L, Trentin L, Becker KA, Frezzato F, Zoratti M, Semenzato G, Gulbins E, Szabo I. Leanza L, et al. Leukemia. 2013 Aug;27(8):1782-5. doi: 10.1038/leu.2013.56. Epub 2013 Feb 21. Leukemia. 2013. PMID: 23426166 No abstract available.

8

Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines.

Leanza L, O'Reilly P, Doyle A, Venturini E, Zoratti M, Szegezdi E, Szabo I. Leanza L, et al. Curr Pharm Des. 2014;20(2):189-200. doi: 10.2174/13816128113199990032. Curr Pharm Des. 2014. PMID: 23701546

9

Intracellular ion channels and cancer.

Leanza L, Biasutto L, Managò A, Gulbins E, Zoratti M, Szabò I. Leanza L, et al. Front Physiol. 2013 Sep 3;4:227. doi: 10.3389/fphys.2013.00227. Front Physiol. 2013. PMID: 24027528 Free PMC article. Review.

10

Mitochondrial ion channels as oncological targets.

Leanza L, Zoratti M, Gulbins E, Szabo I. Leanza L, et al. Oncogene. 2014 Dec 4;33(49):5569-81. doi: 10.1038/onc.2013.578. Epub 2014 Jan 27. Oncogene. 2014. PMID: 24469031 Review.

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