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Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.
Logsdon DP, Grimard M, Luo M, Shahda S, Jiang Y, Tong Y, Yu Z, Zyromski N, Schipani E, Carta F, Supuran CT, Korc M, Ivan M, Kelley MR, Fishel ML. Logsdon DP, et al. Among authors: supuran ct. Mol Cancer Ther. 2016 Nov;15(11):2722-2732. doi: 10.1158/1535-7163.MCT-16-0253. Epub 2016 Aug 17. Mol Cancer Ther. 2016. PMID: 27535970 Free PMC article.
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.
Lou Y, McDonald PC, Oloumi A, Chia S, Ostlund C, Ahmadi A, Kyle A, Auf dem Keller U, Leung S, Huntsman D, Clarke B, Sutherland BW, Waterhouse D, Bally M, Roskelley C, Overall CM, Minchinton A, Pacchiano F, Carta F, Scozzafava A, Touisni N, Winum JY, Supuran CT, Dedhar S. Lou Y, et al. Among authors: supuran ct. Cancer Res. 2011 May 1;71(9):3364-76. doi: 10.1158/0008-5472.CAN-10-4261. Epub 2011 Mar 17. Cancer Res. 2011. PMID: 21415165
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.
Carta F, Garaj V, Maresca A, Wagner J, Avvaru BS, Robbins AH, Scozzafava A, McKenna R, Supuran CT. Carta F, et al. Among authors: supuran ct. Bioorg Med Chem. 2011 May 15;19(10):3105-19. doi: 10.1016/j.bmc.2011.04.005. Epub 2011 Apr 6. Bioorg Med Chem. 2011. PMID: 21515057
Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation.
Dubois L, Peeters S, Lieuwes NG, Geusens N, Thiry A, Wigfield S, Carta F, McIntyre A, Scozzafava A, Dogné JM, Supuran CT, Harris AL, Masereel B, Lambin P. Dubois L, et al. Among authors: supuran ct. Radiother Oncol. 2011 Jun;99(3):424-31. doi: 10.1016/j.radonc.2011.05.045. Epub 2011 Jun 14. Radiother Oncol. 2011. PMID: 21676479 Free article.
2,095 results