Wu L - Search Results

1

Design, synthesis and evaluation of novel ¹⁹F magnetic resonance sensitive protein tyrosine phosphatase inhibitors.

Li Y, Xia G, Guo Q, Wu L, Chen S, Yang Z, Wang W, Zhang ZY, Zhou X, Jiang ZX. Li Y, et al. Among authors: wu l. Medchemcomm. 2016 Aug 1;7(8):1672-1680. doi: 10.1039/C6MD00277C. Epub 2016 Jun 20. Medchemcomm. 2016. PMID: 27529021 Free PMC article.

2

Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis.

He R, Bai Y, Yu ZH, Wu L, Gunawan AM, Zhang ZY. He R, et al. Among authors: wu l. Medchemcomm. 2014 Oct;5(10):1496-1499. doi: 10.1039/C4MD00099D. Medchemcomm. 2014. PMID: 25505942 Free PMC article.

3

Inhibition of Low Molecular Weight Protein Tyrosine Phosphatase by an Induced-Fit Mechanism.

He R, Wang J, Yu ZH, Zhang RY, Liu S, Wu L, Zhang ZY. He R, et al. Among authors: wu l. J Med Chem. 2016 Oct 13;59(19):9094-9106. doi: 10.1021/acs.jmedchem.6b00993. Epub 2016 Oct 3. J Med Chem. 2016. PMID: 27676368 Free PMC article.

4

Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.

Liu S, Zhou B, Yang H, He Y, Jiang ZX, Kumar S, Wu L, Zhang ZY. Liu S, et al. Among authors: wu l. J Am Chem Soc. 2008 Jul 2;130(26):8251-60. doi: 10.1021/ja711125p. Epub 2008 Jun 4. J Am Chem Soc. 2008. PMID: 18528979 Free PMC article.

5

Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor.

He R, Yu Z, He Y, Zeng LF, Xu J, Wu L, Gunawan AM, Wang L, Jiang ZX, Zhang ZY. He R, et al. Among authors: wu l. ChemMedChem. 2010 Dec 3;5(12):2051-6. doi: 10.1002/cmdc.201000348. ChemMedChem. 2010. PMID: 20957718 Free PMC article.

6

Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.

He Y, Xu J, Yu ZH, Gunawan AM, Wu L, Wang L, Zhang ZY. He Y, et al. Among authors: wu l. J Med Chem. 2013 Feb 14;56(3):832-42. doi: 10.1021/jm301781p. Epub 2013 Jan 25. J Med Chem. 2013. PMID: 23305444 Free PMC article.

7

Hydroxyindole carboxylic acid-based inhibitors for receptor-type protein tyrosine protein phosphatase beta.

Zeng LF, Zhang RY, Bai Y, Wu L, Gunawan AM, Zhang ZY. Zeng LF, et al. Among authors: wu l. Antioxid Redox Signal. 2014 May 10;20(14):2130-40. doi: 10.1089/ars.2013.5463. Epub 2014 Feb 4. Antioxid Redox Signal. 2014. PMID: 24180557 Free PMC article.

8

Highly Potent and Selective N-Aryl Oxamic Acid-Based Inhibitors for Mycobacterium tuberculosis Protein Tyrosine Phosphatase B.

Ruddraraju KV, Aggarwal D, Niu C, Baker EA, Zhang RY, Wu L, Zhang ZY. Ruddraraju KV, et al. Among authors: wu l. J Med Chem. 2020 Sep 10;63(17):9212-9227. doi: 10.1021/acs.jmedchem.0c00302. Epub 2020 Aug 21. J Med Chem. 2020. PMID: 32787087 Free PMC article.

9

Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).

Zhang X, He Y, Liu S, Yu Z, Jiang ZX, Yang Z, Dong Y, Nabinger SC, Wu L, Gunawan AM, Wang L, Chan RJ, Zhang ZY. Zhang X, et al. Among authors: wu l. J Med Chem. 2010 Mar 25;53(6):2482-93. doi: 10.1021/jm901645u. J Med Chem. 2010. PMID: 20170098 Free PMC article.

10

A facile hydroxyindole carboxylic acid based focused library approach for potent and selective inhibitors of Mycobacterium protein tyrosine phosphatase B.

Zeng LF, Xu J, He Y, He R, Wu L, Gunawan AM, Zhang ZY. Zeng LF, et al. Among authors: wu l. ChemMedChem. 2013 Jun;8(6):904-8. doi: 10.1002/cmdc.201300115. Epub 2013 Apr 8. ChemMedChem. 2013. PMID: 23568546 Free PMC article.

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