Rowland A - Search Results

1

A novel approach for the simultaneous quantification of 18 small molecule kinase inhibitors in human plasma: A platform for optimised KI dosing.

van Dyk M, Miners JO, Kichenadasse G, McKinnon RA, Rowland A. van Dyk M, et al. Among authors: rowland a. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 15;1033-1034:17-26. doi: 10.1016/j.jchromb.2016.07.046. Epub 2016 Jul 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27521531

2

In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction.

Rowland A, Elliot DJ, Williams JA, Mackenzie PI, Dickinson RG, Miners JO. Rowland A, et al. Drug Metab Dispos. 2006 Jun;34(6):1055-62. doi: 10.1124/dmd.106.009340. Epub 2006 Mar 24. Drug Metab Dispos. 2006. PMID: 16565174

3

Binding of inhibitory fatty acids is responsible for the enhancement of UDP-glucuronosyltransferase 2B7 activity by albumin: implications for in vitro-in vivo extrapolation.

Rowland A, Gaganis P, Elliot DJ, Mackenzie PI, Knights KM, Miners JO. Rowland A, et al. J Pharmacol Exp Ther. 2007 Apr;321(1):137-47. doi: 10.1124/jpet.106.118216. Epub 2007 Jan 19. J Pharmacol Exp Ther. 2007. PMID: 17237258

4

The "albumin effect" and in vitro-in vivo extrapolation: sequestration of long-chain unsaturated fatty acids enhances phenytoin hydroxylation by human liver microsomal and recombinant cytochrome P450 2C9.

Rowland A, Elliot DJ, Knights KM, Mackenzie PI, Miners JO. Rowland A, et al. Drug Metab Dispos. 2008 May;36(5):870-7. doi: 10.1124/dmd.107.019885. Epub 2008 Feb 6. Drug Metab Dispos. 2008. PMID: 18256202

5

The "albumin effect" and drug glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1 and UGT1A6 activities.

Rowland A, Knights KM, Mackenzie PI, Miners JO. Rowland A, et al. Drug Metab Dispos. 2008 Jun;36(6):1056-62. doi: 10.1124/dmd.108.021105. Epub 2008 Mar 24. Drug Metab Dispos. 2008. PMID: 18362158

6

Characterization of the binding of drugs to human intestinal fatty acid binding protein (IFABP): potential role of IFABP as an alternative to albumin for in vitro-in vivo extrapolation of drug kinetic parameters.

Rowland A, Knights KM, Mackenzie PI, Miners JO. Rowland A, et al. Drug Metab Dispos. 2009 Jul;37(7):1395-403. doi: 10.1124/dmd.109.027656. Epub 2009 Apr 27. Drug Metab Dispos. 2009. PMID: 19398502

7

Application of the fluorescent probe 1-anilinonaphthalene-8-sulfonate to the measurement of the nonspecific binding of drugs to human liver microsomes.

McLure JA, Birkett DJ, Elliot DJ, Williams JA, Rowland A, Miners JO. McLure JA, et al. Among authors: rowland a. Drug Metab Dispos. 2011 Sep;39(9):1711-7. doi: 10.1124/dmd.111.039354. Epub 2011 May 24. Drug Metab Dispos. 2011. PMID: 21610127

8

Effect of albumin on human liver microsomal and recombinant CYP1A2 activities: impact on in vitro-in vivo extrapolation of drug clearance.

Wattanachai N, Tassaneeyakul W, Rowland A, Elliot DJ, Bowalgaha K, Knights KM, Miners JO. Wattanachai N, et al. Among authors: rowland a. Drug Metab Dispos. 2012 May;40(5):982-9. doi: 10.1124/dmd.111.044057. Epub 2012 Feb 13. Drug Metab Dispos. 2012. PMID: 22331994

9

Effects of amino acid substitutions at positions 33 and 37 on UDP-glucuronosyltransferase 1A9 (UGT1A9) activity and substrate selectivity.

Korprasertthaworn P, Rowland A, Lewis BC, Mackenzie PI, Yoovathaworn K, Miners JO. Korprasertthaworn P, et al. Among authors: rowland a. Biochem Pharmacol. 2012 Dec 1;84(11):1511-21. doi: 10.1016/j.bcp.2012.08.026. Epub 2012 Sep 5. Biochem Pharmacol. 2012. PMID: 22981363

10

Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT).

Knights KM, Rowland A, Miners JO. Knights KM, et al. Among authors: rowland a. Br J Clin Pharmacol. 2013 Oct;76(4):587-602. doi: 10.1111/bcp.12086. Br J Clin Pharmacol. 2013. PMID: 23362865 Free PMC article. Review.

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