The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.
Hooli BV, Parrado AR, Mullin K, Yip WK, Liu T, Roehr JT, Qiao D, Jessen F, Peters O, Becker T, Ramirez A, Lange C, Bertram L, Tanzi RE.
Hooli BV, et al.
Neurology. 2014 Oct 7;83(15):1353-8. doi: 10.1212/WNL.0000000000000855. Epub 2014 Sep 3.
Neurology. 2014.
PMID: 25186855
Free PMC article.