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Page 1
Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption.
Lewis CTA, Tabrizian L, Nielsen J, Laitila J, Beck TN, Olsen MS, Ognjanovic MM, Aagaard P, Hokken R, Laugesen S, Ingersen A, Andersen JL, Soendenbroe C, Helge JW, Dela F, Larsen S, Sahl RE, Rømer T, Hansen MT, Frandsen J, Suetta C, Ochala J. Lewis CTA, et al. Among authors: ochala j. J Gen Physiol. 2023 Jul 3;155(7):e202213268. doi: 10.1085/jgp.202213268. Epub 2023 May 25. J Gen Physiol. 2023. PMID: 37227464 Free PMC article.
Remodelling of Skeletal Muscle Myosin Metabolic States in Hibernating Mammals.
Lewis CTA, Melhedegaard EG, Ognjanovic MM, Olsen MS, Laitila J, Seaborne RAE, Gronset MN, Zhang C, Iwamoto H, Hessel AL, Kuehn MN, Merino C, Amigo N, Frobert O, Giroud S, Staples JF, Goropashnaya AV, Fedorov VB, Barnes BM, Toien O, Drew KL, Sprenger RJ, Ochala J. Lewis CTA, et al. Among authors: ochala j. bioRxiv [Preprint]. 2024 Feb 27:2023.11.14.566992. doi: 10.1101/2023.11.14.566992. bioRxiv. 2024. Update in: Elife. 2024 May 16;13:RP94616. doi: 10.7554/eLife.94616. PMID: 38014200 Free PMC article. Updated. Preprint.
Remodeling of skeletal muscle myosin metabolic states in hibernating mammals.
Lewis CTA, Melhedegaard EG, Ognjanovic MM, Olsen MS, Laitila J, Seaborne RAE, Gronset M, Zhang C, Iwamoto H, Hessel AL, Kuehn MN, Merino C, Amigo N, Frobert O, Giroud S, Staples JF, Goropashnaya AV, Fedorov VB, Barnes B, Toien O, Drew K, Sprenger RJ, Ochala J. Lewis CTA, et al. Among authors: ochala j. Elife. 2024 May 16;13:RP94616. doi: 10.7554/eLife.94616. Elife. 2024. PMID: 38752835 Free PMC article.
Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms.
Ochala J, Gustafson AM, Diez ML, Renaud G, Li M, Aare S, Qaisar R, Banduseela VC, Hedström Y, Tang X, Dworkin B, Ford GC, Nair KS, Perera S, Gautel M, Larsson L. Ochala J, et al. J Physiol. 2011 Apr 15;589(Pt 8):2007-26. doi: 10.1113/jphysiol.2010.202044. Epub 2011 Feb 14. J Physiol. 2011. PMID: 21320889 Free PMC article.
Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy.
Ross JA, Levy Y, Ripolone M, Kolb JS, Turmaine M, Holt M, Lindqvist J, Claeys KG, Weis J, Monforte M, Tasca G, Moggio M, Figeac N, Zammit PS, Jungbluth H, Fiorillo C, Vissing J, Witting N, Granzier H, Zanoteli E, Hardeman EC, Wallgren-Pettersson C, Ochala J. Ross JA, et al. Among authors: ochala j. Acta Neuropathol. 2019 Sep;138(3):477-495. doi: 10.1007/s00401-019-02034-8. Epub 2019 Jun 19. Acta Neuropathol. 2019. PMID: 31218456 Free PMC article.
Early clinical and pre-clinical therapy development in Nemaline myopathy.
Fisher G, Mackels L, Markati T, Sarkozy A, Ochala J, Jungbluth H, Ramdas S, Servais L. Fisher G, et al. Among authors: ochala j. Expert Opin Ther Targets. 2022 Oct;26(10):853-867. doi: 10.1080/14728222.2022.2157258. Epub 2022 Dec 26. Expert Opin Ther Targets. 2022. PMID: 36524401 Free article.
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