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Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress.
Hill S, Hirano K, Shmanai VV, Marbois BN, Vidovic D, Bekish AV, Kay B, Tse V, Fine J, Clarke CF, Shchepinov MS. Hill S, et al. Among authors: shchepinov ms. Free Radic Biol Med. 2011 Jan 1;50(1):130-8. doi: 10.1016/j.freeradbiomed.2010.10.690. Epub 2010 Oct 16. Free Radic Biol Med. 2011. PMID: 20955788 Free PMC article.
Site-Specific Deuteration of Polyunsaturated Alkenes.
Smarun AV, Petković M, Shchepinov MS, Vidović D. Smarun AV, et al. Among authors: shchepinov ms. J Org Chem. 2017 Dec 15;82(24):13115-13120. doi: 10.1021/acs.joc.7b02169. Epub 2017 Nov 22. J Org Chem. 2017. PMID: 29131956
Deuterated polyunsaturated fatty acids reduce brain lipid peroxidation and hippocampal amyloid β-peptide levels, without discernable behavioral effects in an APP/PS1 mutant transgenic mouse model of Alzheimer's disease.
Raefsky SM, Furman R, Milne G, Pollock E, Axelsen P, Mattson MP, Shchepinov MS. Raefsky SM, et al. Among authors: shchepinov ms. Neurobiol Aging. 2018 Jun;66:165-176. doi: 10.1016/j.neurobiolaging.2018.02.024. Epub 2018 Mar 5. Neurobiol Aging. 2018. PMID: 29579687 Free PMC article.
FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation.
Gaschler MM, Andia AA, Liu H, Csuka JM, Hurlocker B, Vaiana CA, Heindel DW, Zuckerman DS, Bos PH, Reznik E, Ye LF, Tyurina YY, Lin AJ, Shchepinov MS, Chan AY, Peguero-Pereira E, Fomich MA, Daniels JD, Bekish AV, Shmanai VV, Kagan VE, Mahal LK, Woerpel KA, Stockwell BR. Gaschler MM, et al. Among authors: shchepinov ms. Nat Chem Biol. 2018 May;14(5):507-515. doi: 10.1038/s41589-018-0031-6. Epub 2018 Apr 2. Nat Chem Biol. 2018. PMID: 29610484 Free PMC article.
64 results